Xenograft enriched with autologous bone marrow in inlay reconstructions: A tomographic and histomorphometric study in rabbit calvaria
| Autor: | Lydia Masako Ferreira, Silvana Gaiba de França, Alexandre Alves Pinheiro da Silva, André Antonio Pelegrine, Rafael de Mello e Oliveira, Luiz Roberto Manhães Júnior, Marcelo de Oliveira e Silva, Antonio Carlos Aloise |
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| Přispěvatelé: | Universidade Federal de São Paulo (UNIFESP), Universidade Estadual Paulista (Unesp) |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP International Journal of Biomaterials, Vol 2012 (2012) International Journal of Biomaterials |
| Popis: | Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:27:02Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:42:23Z : No. of bitstreams: 1 2-s2.0-84866250839.pdf: 6275180 bytes, checksum: 94b5c464ae37b08d81f5d2dade098b8b (MD5) Made available in DSpace on 2014-05-27T11:27:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-09-19 Objective. The aim of this study was to evaluate the bone healing after the usage of a scaffold enriched with bone marrow. Study Design. Ten rabbits were divided into 2 groups of 5 animals. Bilateral 12 mm diameter defects were created in the parietal bones. In control group Bio-Oss were inserted in both defects and, in experimental group, Bio-Oss enriched with autologous bone marrow were inserted in both defects. In these two groups, one of the calvarial defects was covered with Bio-Gide. The rabbits were sacrified 8 weeks after surgery and both CT and histomorphometric analysis were done. Results. The CT showed a lower remaining defect area in the experimental group covered with Bio-Gide when compared with control group, with and without Bio-Gide. The histomorphometrics showed no difference between groups regarding the non-vital mineralized tissue area. For vital mineralized tissue area, the experimental group covered with Bio-Gide obtained a higher percentage area when compared with control group, with and without Bio-Gide. For non-mineralized tissue area, the experimental group covered with Bio-Gide obtained a lower percentage area when compared with control group, with and without Bio-Gide. Conclusion. Both autologous bone marrow and membrane can contribute to the enhancement of bone healing. Copyright © 2012 Marcelo de Oliveira e Silva et al. Medicine School Unifesp, Rua Pedro de Toledo, 781-11 andar, 04039-032 São Paulo, SP Unesp Dental School, 04039-032 São José dos Campos, SP Unesp Dental School, 04039-032 São José dos Campos, SP |
| Databáze: | OpenAIRE |
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