Electromechanical effects of cardiac resynchronization therapy during rest and stress in patients with heart failure

Autor: Fredrik Gadler, Cinzia Valzania, Arne Olsson, Frieder Braunschweig, Giuseppe Boriani, Maria J. Eriksson
Přispěvatelé: Valzania C, Gadler F, Eriksson MJ, Olsson A, Boriani G, Braunschweig F.
Rok vydání: 2006
Předmět:
Male
Cardiac output
genetic structures
Dobutamine stress echocardiography
medicine.medical_treatment
Left
Hemodynamics
Ventricular Function
Left
Ventricular Dysfunction
Left
Diastole
Natriuretic Peptide
Brain
Ventricular Dysfunction
Ventricular Function
Cardiac Output
Doppler
Cardiac Pacing
Artificial
Brain
Pulsed
Middle Aged
Echocardiography
Doppler
Treatment Outcome
Echocardiography
Artificial
cardiovascular system
Cardiology
Female
Cardiology and Cardiovascular Medicine
circulatory and respiratory physiology
medicine.drug
Echocardiography
Stress
medicine.medical_specialty
Systole
Rest
Cardiac resynchronization therapy
Aged
Echocardiography
Doppler
Pulsed
Heart Failure
Humans
Stroke Volume
Stress
Natriuretic Peptide
Internal medicine
medicine
In patient
cardiovascular diseases
Rest (music)
business.industry
medicine.disease
Heart failure
Dobutamine
Cardiac Pacing
business
Zdroj: European journal of heart failure. 9(6-7)
ISSN: 1388-9842
Popis: Background: Haemodynamic and functional effects of cardiac resynchronization therapy (CRT) have been studied mostly at rest. CRT effects on left ventricular (LV) dyssynchrony and function during stress have not been evaluated in detail. Aims: We studied the electromechanical effects of CRT at rest and during Dobutamine stress echocardiography (DSE), during active and withheld CRT. Methods: Twenty-one responders to CRT (62±12 yr) were assessed by walking test, quality of life, and BNP with active CRT (“off”) and 2 weeks after pacing withdrawal (“off”). DSE (10 μ/kg/min) was performed both at “on” and “off” to evaluate dyssynchrony parameters, systolic and diastolic function. Results: At rest, CRT withdrawal was associated with an increased interventricular mechanical delay (IVMD, from 21±18 ms to 49±24 ms, p
Databáze: OpenAIRE
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