HLA-DPB1 polymorphism in the Thais of Southeast Asia
| Autor: | Sasitorn Bejrachandra, Dasnayanee Chandanayingyong, Komon Longta, Panpimon Longta, Rapeepun Vangseratthana, Henry A.F. Stephens, Monchan Sirikong, Ekaraj Rungruang, Somboon Lekmak, Lian Fan |
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| Rok vydání: | 1994 |
| Předmět: |
China
HLA-DP Antigens Molecular Sequence Data Immunology Ethnic group Thais Southeast asia parasitic diseases Humans Immunology and Allergy Allele Allele frequency Alleles Asia Southeastern HLA-DP beta-Chains Genetics Polymorphism Genetic Base Sequence biology HLA-DPB1 General Medicine Thailand biology.organism_classification Genetic divergence Geography geographic locations Demography HLA-DP locus |
| Zdroj: | Human Immunology. 40:20-24 |
| ISSN: | 0198-8859 |
| DOI: | 10.1016/0198-8859(94)90017-5 |
| Popis: | In this study we examined DPB1 allele frequencies in five ethnic Thai populations resident in different regions of Thailand and neighboring countries. In contrast to other Asian and Pacific populations such as the Japanese, Chinese, Korean, and Papua New Guineans, where DPB1∗0501 has consistently been shown to be the most frequent allele, NE Thais and Thai-Khmers demonstrate a prevalence of DPB1∗1301. Comparison of DPB1 allele frequencies in the Thais of SE Asia, with known frequencies in the Chinese and Japanese populations of E Asia, would appear to confirm previous calculations of genetic divergence between these Oriental populations. |
| Databáze: | OpenAIRE |
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