| Autor: |
Ryan, McNaughton, Chris, Pieper, Osamu, Sakai, Julie V, Rollins, Xin, Zhang, David N, Kennedy, Jean A, Frazier, Laurie, Douglass, Timothy, Heeren, Rebecca C, Fry, T Michael, O'Shea, Karl K, Kuban, Hernán, Jara, Kelly, Vogt |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Radiology. 304(2) |
| ISSN: |
1527-1315 |
| Popis: |
Background Extremely preterm (EP) birth is associated with higher risks of perinatal white matter (WM) injury, potentially causing abnormal neurologic and neurocognitive outcomes. MRI biomarkers distinguishing individuals with and without neurologic disorder guide research on EP birth antecedents, clinical correlates, and prognoses. Purpose To compare multiparametric quantitative MRI (qMRI) parameters of EP-born adolescents with autism spectrum disorder, cerebral palsy, epilepsy, or cognitive impairment (ie, atypically developing) with those without (ie, neurotypically developing), characterizing sex-stratified brain development. Materials and Methods This prospective multicenter study included individuals aged 14-16 years born EP (Extremely Low Gestational Age Newborns-Environmental Influences on Child Health Outcomes Study, or ELGAN-ECHO). Participants underwent 3.0-T MRI evaluation from 2017 to 2019. qMRI outcomes were compared for atypically versus neurotypically developing adolescents and for girls versus boys. Sex-stratified multiple regression models were used to examine associations between spatial entropy density (SE |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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