Molecular hydrogen: a preventive and therapeutic medical gas for various diseases
| Autor: | Xin-Xin Yin, Ming Yang, Li Ge, Na-Na Yang, Wen-Gang Song |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty selective anti-oxidation business.industry Hydrogen molecule Review preventive and therapeutic applications 03 medical and health sciences gaseous signal modulator 030104 developmental biology Human disease Oncology Family medicine Human medicine Global health medicine business Beneficial effects molecular hydrogen |
| Zdroj: | Oncotarget |
| ISSN: | 1949-2553 |
| DOI: | 10.18632/oncotarget.21130 |
| Popis: | // Li Ge 1 , Ming Yang 2 , Na-Na Yang 3 , Xin-Xin Yin 2 and Wen-Gang Song 4 1 Department of Histology and Embryology, School of Basic Medical Sciences, Taishan Medical University, Tai-an City 271000, Shandong Province, PR China 2 Department of Clinical Medicine, Taishan Medical University, Tai-an City 271000, Shandong Province, PR China 3 Key Laboratory of Atherosclerosis in Universities of Shandong, Taishan Medical University, Institute of Atherosclerosis, Taishan Medical University, Tai-an City 271000, Shandong Province, PR China 4 Department of medical immunology, School of Basic Medical Sciences, Taishan Medical University, Tai-an City 271000, Shandong Province, PR China Correspondence to: Wen-Gang Song, email: s.com@163.com Keywords: molecular hydrogen, selective anti-oxidation, gaseous signal modulator, preventive and therapeutic applications Received: April 27, 2017 Accepted: August 26, 2017 Published: September 21, 2017 ABSTRACT Since the 2007 discovery that molecular hydrogen (H 2 ) has selective antioxidant properties, multiple studies have shown that H 2 has beneficial effects in diverse animal models and human disease. This review discusses H 2 biological effects and potential mechanisms of action in various diseases, including metabolic syndrome, organ injury, and cancer; describes effective H 2 delivery approaches; and summarizes recent progress toward H 2 applications in human medicine. We also discuss remaining questions in H 2 therapy, and conclude with an appeal for a greater role for H 2 in the prevention and treatment of human ailments that are currently major global health burdens. This review makes a case for supporting hydrogen medicine in human disease prevention and therapy. |
| Databáze: | OpenAIRE |
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