The spatial QRS-T angle in the Frank vectorcardiogram: accuracy of estimates derived from the 12-lead electrocardiogram
| Autor: | Charlotte A. Schreurs, Jan A. Kors, Ernst E. van der Wall, Martin J. Schalij, Cees A. Swenne, Annemijn M Algra, Suzanne C. Cannegieter, Sumche Man |
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| Přispěvatelé: | Obstetrics and gynaecology, Medical Informatics |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.diagnostic_test Vectorcardiography 12 lead electrocardiogram Reproducibility of Results Inverse Spatial QRS-T angle Gold standard (test) Middle Aged Sensitivity and Specificity Matrix multiplication predicts cardiac death coronary-heart-disease ventricular repolarization orthogonal electrocardiogram prognostic-significance analysis system normal men population mortality leads Matrix (mathematics) Ventricular Fibrillation Statistics Linear regression medicine Humans Female Diagnosis Computer-Assisted Cardiology and Cardiovascular Medicine Electrodes Algorithms Mathematics |
| Zdroj: | Journal of Electrocardiology, 43(4), 294-301. Churchill Livingstone Schreurs, C A, Algra, A M, Man, S C, Cannegieter, S C, van der Wall, E E, Schalij, M J, Kors, J A & Swenne, C A 2010, ' The spatial QRS-T angle in the Frank vectorcardiogram : accuracy of estimates derived from the 12-lead electrocardiogram ', Journal of Electrocardiology, vol. 43, no. 4, pp. 294-301 . https://doi.org/10.1016/j.jelectrocard.2010.03.009 Journal of Electrocardiology, 43(4), 294-301 |
| ISSN: | 0022-0736 |
| Popis: | Background and Purpose: The spatial QRS-T angle (SA), a predictor of sudden cardiac death, is a vectorcardiographic variable. Gold standard vertorcardiograms (VCGs) are recorded by using the Frank electrode positions. However, with the commonly available 12-lead ECG, VCGs must be synthesized by matrix multiplication (inverse Dower matrix/Kors matrix). Alternatively, Rautaharju proposed a method to calculate SA directly from the 12-lead ECG. Neither spatial angles computed by using the inverse Dower matrix (SA-D) nor by using the Kors matrix (SA-K) or by using Rautaharju's method (SA-R) have been validated with regard to the spatial angles as directly measured in the Frank VCG (SA-F). Our present study aimed to perform this essential validation. Methods: We analyzed SAs in 1220 simultaneously recorded 12-lead ECGs and VCGs, in all data, in SA-F-based tertiles, and after stratification according to pathology or sex. Results: Linear regression of SA-K, SA-D, and SA-R on SA-F yielded offsets of 0.01 degrees, 20.3 degrees, and 28.3 degrees and slopes of 0.96, 0.86, and 0.79, respectively. The bias of SA-K with respect to SA-F (mean +/- SD, -3.2 degrees +/- 13.9 degrees) was significantly (P < .001) smaller than the bias of both SA-D and SA-R with respect to SA-F (8.0 degrees +/- 18.6 degrees and 9.8 degrees +/- 24.6 degrees, respectively); tertile analysis showed a much more homogeneous behavior of the bias in SA-K than of both the bias in SA-D and in SA-R. In pathologic ECGs, there was no significant bias in SA-K; bias in men and women did not differ. Conclusion: SA-K resembled SA-F best. In general, when there is no specific reason either to synthesize VCGs with the inverse Dower matrix or to calculate the spatial QRS-T angle with Rautaharju's method, it seems prudent to use the Kors matrix. (C) 2010 Elsevier Inc. All rights reserved. |
| Databáze: | OpenAIRE |
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