Combined computed tomography and fluorodeoxyglucose positron emission tomography in the diagnosis of prosthetic valve endocarditis: A case series
| Autor: | Fabio Tumietto, Pier Giorgio Scotton, Cristina Nanni, Francesco Cristini, Michele Bartoletti, Silvia Sanfilippo, Rachele Bonfiglioli, Luigi Raumer, Claudio Rapezzi, Pierluigi Viale, Stefano Fanti, Marco Di Eusanio, Giovanni Fasulo, Maddalena Graziosi, Maddalena Giannella |
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| Přispěvatelé: | Bartoletti, M., Tumietto, F., Fasulo, G., Giannella, M., Cristini, F., Bonfiglioli, R., Raumer, L., Nanni, C., Sanfilippo, S., Di Eusanio, M., Scotton, P.G., Graziosi, M., Rapezzi, C., Fanti, S., Viale, P. |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Aortic valve Fluorine Radioisotopes Case Report Multimodal Imaging Postoperative Complications Diagnosis FDG-PET Prosthetic valve endocarditis False Negative Reactions Medicine(all) Aged 80 and over Heart Valve Prosthesis Implantation Endocarditis medicine.diagnostic_test Candidiasis General Medicine Middle Aged Combined Modality Therapy medicine.anatomical_structure Positron emission tomography Aortic Valve Heart Valve Prosthesis Female Radiology Tomography Adult Reoperation medicine.medical_specialty Prosthesis-Related Infections General Biochemistry Genetics and Molecular Biology NO Fluorodeoxyglucose F18 medicine Humans Thrombus Aged Biochemistry Genetics and Molecular Biology(all) business.industry FDG-PET Prosthetic valve endocarditis Diagnosis Duke’s criteria Endocarditis Bacterial Gold standard (test) medicine.disease Duke’s criteria Positron-Emission Tomography Radiopharmaceuticals Tomography X-Ray Computed business |
| Zdroj: | BMC Research Notes |
| Popis: | Background: The diagnosis of prosthetic valve endocarditis is challenging. The gold standard for prosthetic valve endocarditis diagnosis is trans-esophageal echocardiography. However, trans-esophageal echocardiography may result in negative findings or yield images difficult to differentiate from thrombus in patients with prosthetic valve endocarditis. Combined computed tomography and fluorodeoxyglucose positron emission tomography is a potentially promising diagnostic tool for several infectious conditions and it has also been employed in patients with prosthetic valve endocarditis but data are still scant. Case presentations. We reviewed the charts of 6 patients with prosthetic aortic valves evaluated for suspicion of prosthetic valve endocarditis, at two different hospital, over a 3-year period. We found 3 patients with early-onset PVE cases and blood cultures yielding Pseudomonas aeruginosa, Staphylococcus epidermidis and Staphylococcus lugdunensis, respectively; and 3 late-onset cases in the remaining 3 patients with isolation in the blood of Streptococcus bovis, Candida albicans and P. aeruginosa, respectively. Initial trans-esophageal echocardiography was negative in all the patients, while fluorodeoxyglucose positron emission tomography showed images suspicious for prosthetic valve endocarditis. In 4 out of 6 patients valve replacement was done with histology confirming the prosthetic valve endocarditis diagnosis. After an adequate course of antibiotic therapy fluorodeoxyglucose positron emission tomography showed resolution of prosthetic valve endocarditis in all the patients. Conclusion: Our experience confirms the potential role of fluoroseoxyglucose positron emission tomography in the diagnosis and follow-up of prosthetic valve endocarditis. © 2014 Bartoletti et al.; licensee BioMed Central Ltd. |
| Databáze: | OpenAIRE |
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