Role of capsule endoscopy in alarm features and non-responsive celiac disease: A European multicenter study
| Autor: | Cristina Carretero-Ribón, Juan-Manuel Herrerıas-Gutierrez, Juan Egea-Valenzuela, Javier Sempere-Garcia-Argüelles, Ignacio Fernandez-Urien-Sainz, Begoña González-Suárez, Antonio López-Higueras, Federico Argüelles-Arias, Javier Garcıa-Lledo, Vicente Pons-Beltrán, Enrique Pérez-Cuadrado-Robles, Enrique Pérez-Cuadrado-Martínez, Santiago Gonzalez-Vazquez, Mileidis San Juan-Acosta, Pilar Borque-Barrera, Federica Branchi, Marisol Luján-Sanchis, Jose-Francisco Juanmartinena-Fernandez, Victoria-Alejandra Jimenez-Garcıa, Francisco Sanchez-Ceballos, Lucıa Ruano-Dıaz, Bruno Rosa, Luca Elli, Noelia Alonso-Lázaro, Julio Valle-Muñoz, Sofia Xavier |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Disease Gastroenterology Capsule Endoscopy Risk Assessment Severity of Illness Index law.invention Cohort Studies 03 medical and health sciences Diet Gluten-Free Young Adult 0302 clinical medicine Intestinal mucosa Capsule endoscopy law Internal medicine Severity of illness Intestine Small medicine Humans Radiology Nuclear Medicine and imaging Young adult Intestinal Mucosa Retrospective Studies business.industry Retrospective cohort study Middle Aged medicine.disease Lymphoma Celiac Disease 030220 oncology & carcinogenesis Disease Progression 030211 gastroenterology & hepatology Female business Cohort study Follow-Up Studies |
| Zdroj: | Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. 30(4) |
| ISSN: | 1443-1661 |
| Popis: | Background and aim The role of capsule endoscopy (CE) in established celiac disease (CD) remains unclear. Our objective was to analyze the usefulness of CE in the suspicion of complicated CD. Methods This was a retrospective multicenter study. One hundred and eighty-nine celiac patients (mean age: 46.6 ± 16.6, 30.2% males) who underwent CE for alarm symptoms (n = 86, 45.5%) or non-responsive CD (n = 103, 54.5%) were included. Diagnostic yield (DY), therapeutic impact and safety were analyzed. Results Capsule endoscopy was completed in 95.2% of patients (small bowel transit time: 270.5 ± 100.2 min). Global DY was 67.2%, detecting atrophic mucosa (n = 92, 48.7%), ulcerative jejunoileitis (n = 21, 11.1%), intestinal lymphoma (n = 7, 3.7%) and other enteropathies (n = 7, 3.7%, six Crohn's disease cases and one neuroendocrine tumor). The DY of CE was significantly higher in patients presenting with non-responsive disease compared to patients with alarm symptoms (73.8% vs 59.3%, P = 0.035). The new findings of the CE modified management in 59.3% of the cases. There were no major complications. Conclusion Capsule endoscopy may be a moderately helpful and safe diagnostic tool in the suspicion of complicated CD, modifying the clinical course of these patients. |
| Databáze: | OpenAIRE |
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