Differences in airway lumen area between supine and upright computed tomography in patients with chronic obstructive pulmonary disease

Autor:	Shiho Matsuoka, Hidehiro Irie, Wakako Yamasawa, Mitsuru Murata, Yoichi Yokoyama, Masahiro Jinzaki, Yoshitake Yamada, Koichi Fukunaga, Shotaro Chubachi, Yuki Niijima, Akiko Tanabe, Minoru Yamada
Rok vydání:	2021
Předmět:	Male medicine.medical_specialty Supine position Lumen (anatomy) Patient Positioning 030218 nuclear medicine & medical imaging Pulmonary function testing Inspiratory Capacity Breath Holding 03 medical and health sciences Pulmonary Disease Chronic Obstructive 0302 clinical medicine Predictive Value of Tests Internal medicine mental disorders Multidetector Computed Tomography medicine Supine Position Humans COPD Lung volumes Expiration Prospective Studies Lung Aged lcsh:RC705-779 Aged 80 and over business.industry Research Pulmonary function test Reproducibility of Results lcsh:Diseases of the respiratory system Airway obstruction respiratory system medicine.disease 030228 respiratory system Standing Position Cardiology Female business psychological phenomena and processes CT
Zdroj:	Respiratory Research Respiratory Research, Vol 22, Iss 1, Pp 1-9 (2021)
ISSN:	1465-993X 0000-2658
Popis:	Background No clinical studies to date have compared the inspiratory and expiratory airway lumen area between supine and standing positions. Thus, the aims of this study were twofold: (1) to compare inspiratory and expiratory airway lumen area (IAA and EAA, respectively) on computed tomography (CT) among supine and standing positions; and (2) to investigate if IAA and EAA are associated with lung function abnormality in patients with chronic obstructive pulmonary disease (COPD). Methods Forty-eight patients with COPD underwent both low-dose conventional (supine position) and upright CT (standing position) during inspiration and expiration breath-holds and a pulmonary function test (PFT) on the same day. We measured the IAA and EAA in each position. Results For the trachea to the third-generation bronchi, the IAA was significantly larger in the standing position than in the supine position (4.1–4.9% increase, all p Conclusions Airway lumen areas were larger in the standing position than in the supine position. IAAs reflect airway obstruction, and EAAs reflect lung hyperinflation. Upright CT might reveal these abnormalities more precisely. Trial registration University Hospital Medical Information Network (UMIN 000026587), Registered 17 March 2017. URL: https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000030456.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9763248c4341b8c0ce3209a488585d5e https://pubmed.ncbi.nlm.nih.gov/33789651 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.