Hepatitis C: the complications of immune dysfunction

Autor:	Christopher Trabue, Ellis King, Deling Yin, Zhi Q. Yao, Jonathan P. Moorman
Rok vydání:	2007
Předmět:	Host immunity business.industry Hepatitis C virus Immunology virus diseases Essential mixed cryoglobulinemia Hepatitis C medicine.disease medicine.disease_cause Immune Dysfunction Virology Lymphoma medicine Immunology and Allergy business
Zdroj:	Expert Review of Clinical Immunology. 3:145-157
ISSN:	1744-8409 1744-666X
DOI:	10.1586/1744666x.3.2.145
Popis:	Hepatitis C virus (HCV) infection has been linked to numerous diseases of immune dysfunction, including, but not limited to, essential mixed cryoglobulinemia and non-Hodgkin's lymphoma. Clinical studies support these associations and treatment of the underlying HCV infection has been variably successful. Recent studies, focusing on the role of HCV gene products, have discovered evidence of dysregulated responses in multiple aspects of host immunity that may be contributing to the genesis of these diseases. Novel treatments that target these areas of dysregulation offer hope for improved therapy for the diseases associated with immunodysregulation by HCV.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975a858c2b068c8f41a51f29366b35bd https://doi.org/10.1586/1744666x.3.2.145 Zobrazit plný text záznamu