Simulation of surface strain in tibiofemoral cartilage during walking for the prediction of collagen fibre orientation
| Autor: | Dan Negrut, Darryl G. Thelen, Antonio M. Recuero, Scott C.E. Brandon, Michael F. Vignos, Colin R. Smith, Milad Rakhsha |
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| Rok vydání: | 2018 |
| Předmět: |
Materials science
Surface strain Cartilage Biomedical Engineering Computational Mechanics Articular cartilage 02 engineering and technology Orientation (graph theory) Article Collagen fibre 030218 nuclear medicine & medical imaging Computer Science Applications 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Collagen fibres Split lines 0202 electrical engineering electronic engineering information engineering medicine 020201 artificial intelligence & image processing Radiology Nuclear Medicine and imaging Layer (electronics) Biomedical engineering |
| Zdroj: | Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization. 7:396-405 |
| ISSN: | 2168-1171 2168-1163 |
| Popis: | The collagen fibers in the superficial layer of tibiofemoral articular cartilage exhibit distinct patterns in orientation revealed by split lines. In this study, we introduce a simulation framework to predict cartilage surface loading during walking to investigate if split line orientations correspond with principal strain directions in the cartilage surface. The two-step framework uses a multibody musculoskeletal model to predict tibiofemoral kinematics which are then imposed on a deformable surface model to predict surface strains. The deformable surface model uses absolute nodal coordinate formulation (ANCF) shell elements to represent the articular surface and a system of spring-dampers and internal pressure to represent the underlying cartilage. Simulations were performed to predict surface strains due to osmotic pressure, loading induced by walking, and the combination of both loading due to pressure and walking. Time-averaged magnitude-weighted first principal strain directions agreed well with split line maps from the literature for both the osmotic pressure and combined cases. This result suggests there is indeed a connection between collagen fiber orientation and mechanical loading, and indicates the importance of accounting for the pre-strain in the cartilage surface due to osmotic pressure. |
| Databáze: | OpenAIRE |
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