Synthesis of seven-membered lactones by regioselective and stereoselective iodolactonization of electron-deficient olefins

Autor:	Zhuofeng Ke, Pan-Ting Tang, Ming Li, Liang-Neng Wang, Youxiang Shao, Xiao-Peng Luo, Yue-Jin Liu, Zeng Minghua, Ni-Juan Zhang, Yi Wei
Rok vydání:	2020
Předmět:	Stereochemistry Chemistry Materials Chemistry Metals and Alloys Ceramics and Composites Iodolactonization Regioselectivity Stereoselectivity General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Chemical Communications. 56:6680-6683
ISSN:	1364-548X 1359-7345
Popis:	A regio- and stereoselective iodolactonization of internal electron-deficient olefinic acids has been reported, which provides a straightforward access to a series of multi-functionalized seven-membered lactones containing two consecutive chiral centers. The ester substituents on the olefins played a key role in achieving high regioselectivity. This result was proved through experiments and DFT calculations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974b101230805db16012e767d1ad3071 https://doi.org/10.1039/c9cc10080f Zobrazit plný text záznamu