Periodontal diseases and carotid intima-media thickness in Bangladesh
| Autor: | Golam Sarwar, Ryan T. Demmer, Tatjana Rundek, Moïse Desvarieux, Alauddin Ahmed, Ishrat Shaheen, Mahbub Eunus, Habibul Ahsan, Tariqul Islam, Faruque Parvez, Nur Mohammad Habibullah, Nafiz Ahsan, Fen Wu, Yu Chen, Rina Rani Paul |
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| Rok vydání: | 2016 |
| Předmět: |
Carotid Artery Diseases
Longitudinal study medicine.medical_specialty Cross-sectional study Population 030204 cardiovascular system & hematology Carotid Intima-Media Thickness Gastroenterology Article 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Humans Medicine Longitudinal Studies Prospective Studies Prospective cohort study education Periodontal Diseases Bangladesh education.field_of_study business.industry 030206 dentistry Middle Aged Atherosclerosis Cross-Sectional Studies Quartile Intima-media thickness Clinical attachment loss Periodontics business Body mass index |
| Zdroj: | Journal of Clinical Periodontology. 43:909-917 |
| ISSN: | 0303-6979 |
| DOI: | 10.1111/jcpe.12597 |
| Popis: | AIM To evaluate the relationship between periodontal diseases and subclinical atherosclerosis in a younger and lean South Asian population. METHODS We conducted a cross-sectional study in 917 subjects (mean age 46 years and mean body mass index 21.1 kg/m2 ) from the Health Effects of Arsenic Longitudinal Study in Bangladesh. Multivariate linear regression models were used to assess the associations between multiple clinical measures of periodontal diseases and carotid intima-media thickness (IMT). RESULTS Mean attachment loss (AL) and percentage of sites with AL ≥ 4 mm (% AL ≥ 4) were associated with increased IMT. The IMT was 20.0-μm (95% CI: 2.2, 37.8) and 26.5-μm (95% CI: 8.9, 44.1) higher in subjects in the top quartile of mean AL (>3.72 mm) and % AL ≥ 4 (>58.4%), respectively, compared to those in the bottom quartile. In a subset of 366 subjects, mean AL was positively associated with plasma levels of matrix metalloproteinase-9 (p |
| Databáze: | OpenAIRE |
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