The aging immune system and its relationship with cancer
| Autor: | Ronald E. Gress, Anthony D Foster, Amogh Sivarapatna |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
business.industry
Incidence (epidemiology) T cell animal diseases Immune senescence Cancer chemical and pharmacologic phenomena General Medicine biochemical phenomena metabolism and nutrition medicine.disease Article Immune system medicine.anatomical_structure Immunity Immunology Medicine bacteria Geriatrics and Gerontology business |
| Zdroj: | Aging health. 7(5) |
| ISSN: | 1745-509X |
| Popis: | The incidence of most common cancers increases with age. This occurs in association with, and is possibly caused by a decline in immune function, termed immune senescence. Although the size of the T-cell compartment is quantitatively maintained into older age, several deleterious changes (including significant changes to T-cell subsets) occur over time that significantly impair immunity. This article highlights some of the recent findings regarding the aging immune system, with an emphasis on the T-cell compartment and its role in cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|