The Prospective Studies of Atherosclerosis (Proof-ATHERO) Consortium: Design and Rationale

Autor: Zhiyong Zou, Dorota A. Zozulińska-Ziółkiewicz, Raffaele Izzo, Lena Tschiderer, Manuel F. Landecho, Kuo Liong Chien, Stefan Kiechl, Damiano Baldassarre, Matthias W. Lorenz, Tatjana Rundek, Mario Fritsch Neves, Jing Liu, Dirk Sander, Caroline Schmidt, Matthew Walters, Enrique Bernal, Gulay Asci, Rafael Gabriel, Michiel L. Bots, Bernhard Iglseder, Eric de Groot, Hirokazu Honda, Mark A. Espeland, Grace Parraga, Joline W.J. Beulens, Paolo Gresele, Pythia T. Nieuwkerk, Dianna Magliano, Michael J. Sweeting, Lars Lind, Kostas Kapellas, Tomi-Pekka Tuomainen, Maryam Kavousi, Frank P. Brouwers, Jean Philippe Empana, Markolf Hanefeld, Shuhei Okazaki, Menno V. Huisman, Jang Ho Bae, Daniel Staub, Aikaterini Papagianni, Gerhard Klingenschmid, Lisa Seekircher, Peter Willeit, Prabath W.B. Nanayakkara, Jackie F. Price, Johann Willeit, Radojica Stolić, Akihiko Kato, Alberico L. Catapano, Naveed Sattar, Christopher D. Byrne, Göran Bergström, Laura Calabresi, Robert Ekart, Michael H. Olsen, Michiaki Nagai, Michiel A. Van Agtmael, Marat Ezhov, Stefan Agewall, Eiichi Sato, Miles D. Witham, Eva Lonn
Přispěvatelé: Ege Üniversitesi, Epidemiology, Internal medicine, Epidemiology and Data Science, ACS - Diabetes & metabolism, APH - Health Behaviors & Chronic Diseases, ACS - Heart failure & arrhythmias, Tschiderer, Lena, Seekircher, Lisa, Klingenschmid, Gerhard, Izzo, Raffaele, Baldassarre, Damiano, Iglseder, Bernhard, Calabresi, Laura, Liu, Jing, Price, Jackie F, Bae, Jang-Ho, Brouwers, Frank P, de Groot, Eric, Schmidt, Caroline, Bergström, Göran, Aşçi, Gülay, Gresele, Paolo, Okazaki, Shuhei, Kapellas, Kosta, Landecho, Manuel F, Sattar, Naveed, Agewall, Stefan, Zou, Zhi-Yong, Byrne, Christopher D, Nanayakkara, Prabath W B, Papagianni, Aikaterini, Witham, Miles D, Bernal, Enrique, Ekart, Robert, van Agtmael, Michiel A, Neves, Mario F, Sato, Eiichi, Ezhov, Marat, Walters, Matthew, Olsen, Michael H, Stolić, Radojica, Zozulińska-Ziółkiewicz, Dorota A, Hanefeld, Markolf, Staub, Daniel, Nagai, Michiaki, Nieuwkerk, Pythia T, Huisman, Menno V, Kato, Akihiko, Honda, Hirokazu, Parraga, Grace, Magliano, Dianna, Gabriel, Rafael, Rundek, Tatjana, Espeland, Mark A, Kiechl, Stefan, Willeit, Johann, Lind, Lar, Empana, Jean Philippe, Lonn, Eva, Tuomainen, Tomi-Pekka, Catapano, Alberico, Chien, Kuo-Liong, Sander, Dirk, Kavousi, Maryam, Beulens, Joline W J, Bots, Michiel L, Sweeting, Michael J, Lorenz, Matthias W, Willeit, Peter, Austrian Science Fund, Gastroenterology and Hepatology, Medical Psychology, APH - Mental Health, APH - Personalized Medicine, Amsterdam Gastroenterology Endocrinology Metabolism
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Gerontology, 66(5), 447-459. KARGER
Gerontology, 66(5), 447-459. Karger
Gerontology, 66(5), 447-459. S. Karger AG
Tschiderer, L, Seekircher, L, Klingenschmid, G, Izzo, R, Baldassarre, D, Iglseder, B, Calabresi, L, Liu, J, Price, J F, Bae, J H, Brouwers, F P, de Groot, E, Schmidt, C, Bergström, G, Aşçi, G, Gresele, P, Okazaki, S, Kapellas, K, Landecho, M F, Sattar, N, Agewall, S, Zou, Z Y, Byrne, C D, Nanayakkara, P W B, Papagianni, A, Witham, M D, Bernal, E, Ekart, R, van Agtmael, M A, Neves, M F, Sato, E, Ezhov, M, Walters, M, Olsen, M H, Stolić, R, Zozulińska-Ziółkiewicz, D A, Hanefeld, M, Staub, D, Nagai, M, Nieuwkerk, P T, Huisman, M V, Kato, A, Honda, H, Parraga, G, Magliano, D, Gabriel, R, Rundek, T, Espeland, M A, Kiechl, S, Willeit, J & Proof-ATHERO Study Group 2020, ' The Prospective Studies of Atherosclerosis (Proof-ATHERO) Consortium : Design and Rationale ', Gerontology, vol. 66, no. 5, pp. 447-459 . https://doi.org/10.1159/000508498
2020, ' The Prospective Studies of Atherosclerosis (Proof-ATHERO) Consortium: Design and Rationale ', Gerontology, pp. 1-13 . https://doi.org/10.1159/000508498
Tschiderer, L, Seekircher, L, Klingenschmid, G, Izzo, R, Baldassarre, D, Iglseder, B, Calabresi, L, Liu, J, Price, J F, Bae, J H, Brouwers, F P, De Groot, E, Schmidt, C, Bergström, G, Aşçi, G, Gresele, P, Okazaki, S, Kapellas, K, Landecho, M F, Sattar, N, Agewall, S, Zou, Z Y, Byrne, C D, Nanayakkara, P W B, Papagianni, A, Witham, M D, Bernal, E, Ekart, R, Van Agtmael, M A, Neves, M F, Sato, E, Ezhov, M, Walters, M, Olsen, M H, Stolić, R, Zozulińska-Ziółkiewicz, D A, Hanefeld, M, Staub, D, Nagai, M, Nieuwkerk, P T, Huisman, M V, Kato, A, Honda, H, Parraga, G, Magliano, D, Gabriel, R, Rundek, T, Espeland, M A, Kiechl, S, Willeit, J, Lind, L, Empana, J P, Lonn, E, Tuomainen, T P, Catapano, A, Chien, K L, Sander, D, Kavousi, M, Beulens, J W J, Bots, M L, Sweeting, M J, Lorenz, M W & Willeit, P 2020, ' The Prospective Studies of Atherosclerosis (Proof-ATHERO) Consortium : Design and Rationale ', Gerontology, vol. 66, no. 5, pp. 447-459 . https://doi.org/10.1159/000508498
ISSN: 0304-324X
DOI: 10.1159/000508498
Popis: Atherosclerosis - the pathophysiological mechanism shared by most cardiovascular diseases - can be directly or indirectly assessed by a variety of clinical tests including measurement of carotid intima-media thickness, carotid plaque, ankle-brachial index, pulse wave velocity, and coronary artery calcium. the Prospective Studies of Atherosclerosis (Proof-ATHERO) consortium (https://clinicalepi.i-med.ac.at/research/proof-athero/) collates de-identified individual-participant data of studies with information on atherosclerosis measures, risk factors for cardiovascular disease, and incidence of cardiovascular diseases. It currently comprises 74 studies that involve 106,846 participants from 25 countries and over 40 cities. in summary, 21 studies recruited participants from the general population (n = 67,784), 16 from high-risk populations (n = 22,677), and 37 as part of clinical trials (n = 16,385). Baseline years of contributing studies range from April 1980 to July 2014; the latest follow-up was until June 2019. Mean age at baseline was 59 years (standard deviation: 10) and 50% were female. Over a total of 830,619 person-years of follow-up, 17,270 incident cardiovascular events (including coronary heart disease and stroke) and 13,270 deaths were recorded, corresponding to cumulative incidences of 2.1% and 1.6% per annum, respectively. the consortium is coordinated by the Clinical Epidemiology Team at the Medical University of Innsbruck, Austria. Contributing studies undergo a detailed data cleaning and harmonisation procedure before being incorporated in the Proof-ATHERO central database. Statistical analyses are being conducted according to pre-defined analysis plans and use established methods for individual-participant data meta-analysis. Capitalising on its large sample size, the multi-institutional collaborative Proof-ATHERO consortium aims to better characterise, understand, and predict the development of atherosclerosis and its clinical consequences. (c) 2020 S. Karger AG, Basel
Austrian Science Fund (FWF)Austrian Science Fund (FWF) [P 32488]; Dr.-Johannes-and-Hertha-Tuba Foundation
This work was funded by the Austrian Science Fund (FWF) (P 32488) and the Dr.-Johannes-and-Hertha-Tuba Foundation. Funders of individual studies contributing to the present analysis arelisted onthe Proof-ATHERO webpage(https://clinicalepi.i-med.ac.at/research/proof-athero/studies/).
Databáze: OpenAIRE
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