Incidence of ceftriaxone-associated gallbladder pseudolithiasis
| Autor: | Papadopoulou, F., Efremidis, S., Karyda, S., Badouraki, M., Karatza, E., Panteliadis, C., Malaka, K. |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Time Factors Adolescent Infant Newborn Infant General Medicine Urinary Bladder/ultrasonography Cholelithiasis/*chemically induced/ultrasonography Child Preschool Pediatrics Perinatology and Child Health Humans Female Prospective Studies Cephalosporins/administration & dosage/*adverse effects/therapeutic use Child Ceftriaxone/administration & dosage/*adverse effects/therapeutic use |
| Zdroj: | Acta Paediatrica. 88:1352-1355 |
| ISSN: | 0803-5253 |
| DOI: | 10.1111/j.1651-2227.1999.tb01050.x |
| Popis: | We prospectively evaluated the incidence of gallbladder pseudolithiasis in children treated with high doses of ceftriaxone for a variety of serious infections. We also monitored the time interval needed for this phenomenon to develop and resolve completely after initiation and cessation of treatment, respectively. Included in this study are 44 children treated with ceftriaxone 100 mg/kg/d divided into 2 equal intravenous doses and followed by serial abdominal sonography. Eleven children developed pseudolithiasis of gallbladder 2-9 d after initiation of ceftriaxone therapy. Six children (54.5%) developed this complication within the first 3 d. Lithiasis completely resolved 8-23 d after the end of treatment. In conclusion, pseudolithiasis of the gallbladder developed in 25% of sick children and completely resolved in all patients. Early development of this complication was not exceptional. It occurred in more than half of these children. Acta Paediatr |
| Databáze: | OpenAIRE |
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