Mupirocin Resistance: Clinical and Molecular Epidemiology
| Autor: | Teresa M. Morton, Carol A. Kauffman, Suzanne F. Bradley, Mary A. Ramsey |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Microbiology (medical)
Staphylococcus aureus medicine.medical_specialty Epidemiology medicine.drug_class Antibiotics Mupirocin Microbial Sensitivity Tests Drug resistance medicine.disease_cause Microbiology Novel gene chemistry.chemical_compound medicine Humans Antibacterial agent Molecular epidemiology business.industry Drug Resistance Microbial Staphylococcal Infections Bacterial Typing Techniques Surgery Mupirocin resistance Infectious Diseases chemistry Mutation lipids (amino acids peptides and proteins) business |
| Zdroj: | Infection Control and Hospital Epidemiology. 16:354-358 |
| ISSN: | 1559-6834 0899-823X |
| DOI: | 10.1086/647125 |
| Popis: | The antistaphylococcal activity of topical mupirocin has made it an attractive agent for the treatment of asymptomatic colonization with Staphylococcus aureus. Increasing use has been associated with the emergence of mupirocin resistance in staphyloccoci, and failure of therapy has been associated with the isolation of strains exhibiting high-level resistance (MIC > 500 micrograms/mL). Fortunately, low-level mupirocin resistance (MIC < 100 micrograms/mL) occurs most commonly. Because a novel gene encoding for mupirocin resistance resides in both low-level and high-level resistant strains, the emergence of low-level mupirocin resistance may not be as epidemiologically insignificant as previously thought. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|