A guide for assessing the clinical relevance of findings in small bowel capsule endoscopy:Analysis of 8064 answers of international experts to an illustrated script questionnaire
| Autor: | Gabriel Rahmi, John N. Plevris, Charles Houdeville, I. Fernandez-Urien Sainz, Cynthia Li, Cristiano Spada, Philippe Marteau, Anastasios Koulaouzidis, M. Keuchel, M. Robaszkiewicz, Jean-Christophe Saurin, Reena Sidhu, Romain Leenhardt, Rami Eliakim, Ervin Toth, Emanuele Rondonotti, Bruno Rosa, Xavier Dray, Mark E. McAlindon, Deirdre McNamara |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
small bowel bleeding capsule endoscopy Constriction Pathologic Capsule Endoscopy law.invention 03 medical and health sciences 0302 clinical medicine Capsule endoscopy law inflammatory bowel disease Surveys and Questionnaires Intestine Small medicine Humans Clinical significance Retrospective Studies Median score Hepatology business.industry General surgery Angiectasia Gastroenterology medicine.disease Occult Stenosis small bowel endoscopy 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Gastrointestinal Hemorrhage business Variable number Obscure gastrointestinal bleeding |
| Zdroj: | Leenhardt, R, Koulaouzidis, A, McNamara, D, Keuchel, M, Sidhu, R, McAlindon, M, Saurin, J-C, Eliakim, A, Sainz, I F-U, Plevris, J, Rahmi, G, Rondonatti, E, Rosa, B, Spada, C, Toth, E, Houdeville, C, Li, C, Robaszkiewicz, M, Marteau, P & Dray, X 2021, ' A guide for assessing the clinical relevance of findings in small bowel capsule endoscopy : Analysis of 8064 answers of international experts to an illustrated script questionnaire ', Clinics and Research in Hepatology and Gastroenterology, vol. 45, no. 6, 101637 . https://doi.org/10.1016/j.clinre.2021.101637 |
| DOI: | 10.1016/j.clinre.2021.101637 |
| Popis: | Background and aimAlthough recommended, the P-score used for assessing the pertinence / relevance of findings seen in small bowel (SB) capsule endoscopy (CE) is based on a low level of knowledge. The aim of this study was to evaluate the clinical relevance of the most frequent SBCE findings through an illustrated script questionnaire.Materials and MethodsSixteen types of SBCE findings were illustrated four times each in three different settings (occult and overt obscure gastrointestinal bleeding and suspected Crohn's disease), and with a variable number (n = 1/n = 2–5/n ≥ 6), thus providing a questionnaire with 192 scenarios and 576 illustrated questions. Fifteen international experts were asked to rate the finding's relevance for each question as very unlikely (−2) / unlikely (−1) / doubtful (0) / likely (+1) / very likely (+2). The median score (≤−0.75, between -0.75 and 0.75, or ≥0.75) obtained for each scenario determined a low (P0), intermediate (P1) or high (P2) relevance, respectively.Results8064 answers were analyzed. Participation and completion rates were 93% and 100%, respectively. In overt or occult OGIB, resultant P2 findings were 'typical angiectasia', 'deep ulceration', 'stenosis', and'blood', whatever their numbers, and 'superficial ulcerations' when multiple. While in suspected CD, consensus P2 lesions were 'deep ulceration' and 'stenosis' whatever their numbers, and 'aphthoid erosions' and 'superficial ulcerations' when multiple.ConclusionThis study establishes a guide for the evaluation of relevance of SBCE findings. It represents a step forward for SB-CE interpretation and is intended to be used as a tool for teaching and academic research. |
| Databáze: | OpenAIRE |
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