Construct Validity of the Steep Ramp Test for Assessing Cardiorespiratory Fitness in Patients With Breast Cancer and the Effect of Chemotherapy-Related Symptom Burden
| Autor: | Hester J. Van de Wiel, Wim G. Groen, Caroline S. Kampshoff, Laurien M. Buffart, Willem van Mechelen, Goof Schep, Gabe S. Sonke, Rosalie Huijsmans, Wim H. van Harten, Neil K. Aaronson, Martijn M. Stuiver |
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| Přispěvatelé: | Master Evidence Based Practice, APH - Health Behaviors & Chronic Diseases, APH - Quality of Care, CCA - Cancer Treatment and Quality of Life, Public and occupational health, APH - Societal Participation & Health, Rehabilitation medicine, Health Technology & Services Research, APH - Mental Health |
| Rok vydání: | 2022 |
| Předmět: |
Vomiting
Rehabilitation Pain Physical Therapy Sports Therapy and Rehabilitation Nausea n/a OA procedure Exercise Therapy Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] Oxygen Consumption Cross-Sectional Studies All institutes and research themes of the Radboud University Medical Center Cardiorespiratory Fitness Quality of Life Exercise Test Humans Female Breast neoplasms Fatigue |
| Zdroj: | Archives of physical medicine and rehabilitation, 103(12), 2362-2367. W.B. Saunders Ltd Archives of Physical Medicine and Rehabilitation. W.B. Saunders Ltd Archives of physical medicine and rehabilitation, 103, 2362-2367. W.B. Saunders Ltd Archives of Physical Medicine and Rehabilitation, 103, 2362-2367 Archives of Physical Medicine and Rehabilitation, 103, 12, pp. 2362-2367 de Wiel, H J V, Groen, W G, Kampshoff, C S, Buffart, L M, van Mechelen, W, Schep, G, Sonke, G S, Huijsmans, R, van Harten, W H, Aaronson, N K & Stuiver, M M 2022, ' Construct Validity of the Steep Ramp Test for Assessing Cardiorespiratory Fitness in Patients With Breast Cancer and the Effect of Chemotherapy-Related Symptom Burden ', Archives of Physical Medicine and Rehabilitation, vol. 103, no. 12, pp. 2362-2367 . https://doi.org/10.1016/j.apmr.2022.05.014 Archives of Physical Medicine and Rehabilitation, 103(12), 2362-2367. W.B. Saunders Ltd |
| ISSN: | 0003-9993 |
| DOI: | 10.1016/j.apmr.2022.05.014 |
| Popis: | Objective: To investigate the construct validity of the Steep Ramp Test (SRT) by longitudinally comparing the correlation between maximum short exercise capacity of the SRT and direct measurements of peak oxygen consumption (VO 2peak) during or shortly after treatment in patients with breast cancer and the potential effect of chemotherapy-induced symptom burden. Design: Cross-sectional. Setting: Multicenter. Participants: We used data from 2 studies that included women with breast cancer treated with chemotherapy, resulting in 274 observations. A total of 161 patients (N=161) performed the cardiopulmonary exercise test and the SRT in 2 test sessions on different time points around chemotherapy treatment. Interventions: Not applicable. Main Outcome Measures: Fatigue was assessed with the Multidimensional Fatigue Inventory, and nausea and vomiting and pain by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. The longitudinal correlation between the maximum short exercise capacity and VO 2peak was investigated using a linear mixed model. Interaction terms were added to the model to investigate whether the correlation varied by symptom burden. Results: We found a statistically significant moderate correlation between VO 2peak and maximum short exercise capacity (0.61; 95% confidence interval, 0.51-0.70; P2peak with the maximum short exercise capacity with increasing symptom burden. Pain and fatigue did not significantly modify the correlation. Conclusions: The SRT can only be used as a proxy for changes in aerobic capacity with great caution and with attention for the level of nausea and vomiting. |
| Databáze: | OpenAIRE |
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