Receptor mechanisms in fish chromatophores—VIII. Mediated by beta adrenoceptors, catecholamines always act to disperse pigment in siluroid melanophores
| Autor: | Oshima Noriko, Fujii Ryozo, Miyashita Yoko |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
medicine.medical_specialty
Adrenergic receptor Immunology Melanophores Stimulation Endogeny Biology Melanophore chemistry.chemical_compound Catecholamines Internal medicine Receptors Adrenergic beta medicine Animals Chromatophores Neurotransmitter Skin Melanosome Pharmacology integumentary system Electric Conductivity Fishes Isoproterenol Pigments Biological Propranolol Chromatophore Electric Stimulation Cell biology Endocrinology chemistry Catecholamine medicine.drug |
| Zdroj: | Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 81:1-6 |
| ISSN: | 0306-4492 |
| DOI: | 10.1016/0742-8413(85)90082-9 |
| Popis: | 1. The sympathomimetic amines tested, including those of alpha and beta type, were all ineffective in arousing melanosome aggregation within dermal and epidermal melanophores of the siluroid catfish, Parasilurus asotus . 2. Conversely, these amines unfailingly gave rise to a dispersion of the pigment. 3. While alpha-adrenergic blocking agents had only a little influence, beta agents exhibited a strong inhibitory effect on the pigment-dispersing action of the amines. 4. Electrical nervous stimulation failed to bring about a melanosome dispersion. 5. It was concluded that the adrenoceptors possessed by dermal and epidermal melanophores of this species seemed to be solely of the beta-adrenergic type, mediating the pigment dispersion, and that the endogenous amines involved in the darkening reaction of animals may originate in adrenal chromaffin cells, and thus are not derived from the peripheral nervous elements. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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