'B-cell' mitogenicity of carragheenan in mouse
| Autor: | Jean-Pierre Kolb, Geneviève Lespinats, Phuc Canh Quan |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
T-Lymphocytes
Immunology Mice Inbred Strains Stimulation Thymus Gland Biology Carrageenan Lymphocyte Activation Serology Mice chemistry.chemical_compound Species Specificity Bone Marrow medicine Animals Gene B cell B-Lymphocytes Dose-Response Relationship Drug Strain (chemistry) Macrophages Molecular biology In vitro Dextran sulfate medicine.anatomical_structure chemistry Thymidine Spleen |
| Zdroj: | Cellular Immunology. 37:1-13 |
| ISSN: | 0008-8749 |
| Popis: | Carragheenan, a reported toxic agent for macrophages, has been studied for its properties of stimulation of mouse lymphocytes, by measuring the amount of incorporation of tritiated thymidine in cultures of lymphocytes in vitro . Unequivocal evidence has been obtained, concluding that carragheenan selectively activates mouse “B” cells from each strain tested, with the exception of C3H/He mice. Carragheenan probably acts on a subpopulation of B cells different from the populations stimulated by dextran sulfate and LPS. |
| Databáze: | OpenAIRE |
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