A study of chronic pneumonia in a guineapig colony with enzootic Bordetella bronchiseptica infection
Autor: | Margery Wood, A. Baskerville, Margaret Baskerville |
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Rok vydání: | 1982 |
Předmět: |
Pathology
medicine.medical_specialty Pulmonary Fibrosis Guinea Pigs Respiratory System Biology Lymphoid hyperplasia Rodent Diseases Lesion Animals Laboratory otorhinolaryngologic diseases medicine Animals Lung Bordetella Infections Chronic pneumonia Hyperplasia Bordetella bronchiseptica Bacteria General Veterinary Pneumonia respiratory system medicine.disease biology.organism_classification respiratory tract diseases medicine.anatomical_structure biology.protein Enzootic Animal Science and Zoology Lymph Nodes Antibody medicine.symptom Foreign body |
Zdroj: | Laboratory Animals. 16:290-296 |
ISSN: | 1758-1117 0023-6772 |
DOI: | 10.1258/002367782780891787 |
Popis: | Three types of lesion were present in the lungs of guinea pigs with chronic pneumonia - pulmonary interstitial fibrosis, perivascular lymphoid hyperplasia and foreign body granulomas. Bordetella bronchiseptica was present in the nasopharynx, trachea and lungs of a high proportion of animals from 4 weeks old, and antibodies to this organism were also found. Animals removed at 4 days old and reared in isolation from the main colony and free from B. bronchiseptica developed similar lung lesions, so that B. bronchiseptica appeared to have no causative role in these forms of chronic pneumonia. |
Databáze: | OpenAIRE |
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