Classification of ? 1-antitrypsin (Pi) phenotypes by isoelectrofocusing

Autor: J.P. Martin, Th. Genz, Hartwig Cleve
Rok vydání: 1977
Předmět:
Zdroj: Human Genetics. 38:325-332
ISSN: 1432-1203
0340-6717
DOI: 10.1007/bf00402159
Popis: Pi phenotypes have been determined by isoelectrofocusing in a sample of 538 healthy individuals from Southern Germany. Further subdivision of the common PiM phenotype is described. A procedure for the delineation of six common subtypes is presented. It is assumed that the six subtypes are determined by three alleles which are provisionally called PiMa, PiMb, and PiMc. Their frequencies in this sample were 0.75, 0.06, and 0.15, respectively.
Databáze: OpenAIRE