| Autor: |
Michael Kneissl, Tim Wernicke, Johannes Schleusener, Martin Guttmann, Martina C. Meinke, Ulrike Winterwerber, Lucas Wittenbecher, Paula Zwicker, Luca Sulmoni, Markus Weyers, Silke B. Lohan, Thomas Filler, Ulrike Woggon, Neysha Lobo-Ploch, Axel Kramer, Claudia Sicher, Johannes Glaab, Hyun Kyong Cho, Frank Mehnke, Sven Einfeldt, Heiko Gundlach, Sylvia Hagedorn |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports |
| ISSN: |
2045-2322 |
| Popis: |
Multiresistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) cause serious postoperative infections. A skin tolerant far-UVC (2. MRSA bacteria in different concentrations on blood agar plates were inactivated with irradiation doses in the range of 15–40 mJ/cm2. Porcine skin irradiated with a dose of 40 mJ/cm2 at 233 nm showed only 3.7% CPD and 2.3% 6-4PP DNA damage. Corresponding irradiation at 254 nm caused 11–14 times higher damage. Thus, the skin damage caused by the disinfectant doses is so small that it can be expected to be compensated by the skin's natural repair mechanisms. LED-based far-UVC lamps could therefore soon be used in everyday clinical practice to eradicate multiresistant pathogens directly on humans. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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