Unexpected diagnosis of basal cell carcinoma in a patient presenting with a secondary location of Leishmania parasites in the skin
| Autor: | Meriem Ben Abid, Imène Ben Abda, Karim Aoun, Karim Bahri, Rym Ben-Abdallah, Aïda Bouratbine, Hela Mdimagh-Kchir, Houda Hammami, E. Siala |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty 030231 tropical medicine Case Report Lesion 03 medical and health sciences Basal cell carcinoma leishmaniasis Leishmania infantum real time PCR skin leishmaniasis 0302 clinical medicine Amphotericin B parasitic diseases Medicine 030212 general & internal medicine biology business.industry Leishmaniasis General Medicine medicine.disease biology.organism_classification Leishmania Lymphatic system Visceral leishmaniasis medicine.symptom business medicine.drug |
| Zdroj: | Pan African Medical Journal; Vol. 34 No. 1 (2019) The Pan African Medical Journal |
| ISSN: | 1937-8688 |
| Popis: | We report here a case of simultaneous cutaneous and visceral manifestations due toLeishmania L. infantumdiagnosed in an immunocompetent adult. We describe a 74-year-old woman from Tunis, Tunisia, who presented a biologically confirmed visceral leishmaniasis infection concomitant with arm ulceration which appeared 2 years before.LeishmaniaDNA was detected by ITS PCR in both buffy coat and dermal scrapping of the arm lesion. Sequencing revealed that the 2 isolated strains corresponded toL. infantumand were 100% identical. The symptoms of visceral leishmaniasis responded to amphotericin B with rapid healing. However, the skin lesion did not improve althoughLeishmaniaPCR on dermal sample became negative. This location is probably secondarily to lymphatic or blood dissemination during the systemic visceral leishmaniasis infection. It would be favored by the inflammatory environment induced by the basal cell carcinoma subsequently diagnosed. |
| Databáze: | OpenAIRE |
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