Recurrent Squamous Cell Carcinoma of the Eyelid Presenting as Trigeminal Neuralgia
| Autor: | Nicole Spitzer, Naazli Shaikh, Leah Strickland, Son H. Ho |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
squamous cell carcinoma
medicine.medical_specialty orbital apex syndrome genetic structures Perineural invasion Dermatology 03 medical and health sciences 0302 clinical medicine Trigeminal neuralgia medicine trigeminal neuralgia business.industry Cranial nerves General Engineering medicine.disease eye diseases body regions Ophthalmology stomatognathic diseases medicine.anatomical_structure Scalp 030221 ophthalmology & optometry Forehead sense organs Eyelid Skin cancer business 030217 neurology & neurosurgery Orbit (anatomy) |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | This paper describes two patients with squamous cell carcinoma (SCC) of the periocular and periorbital skin who presented with trigeminal neuralgia. Both patients had previous cutaneous SCC of the scalp treated successfully with surgical resection but later presented with neuro-ophthalmic findings suggesting perineural invasion (PNI) of SCC. PNI of SCC in the periocular skin or orbit can lead to devastating effects if malignant cells seed into the orbit and adjacent cranial nerves as our two patients developed an orbital apex syndrome. Patients with a history of SCC of the scalp and forehead who later develop neuro-ophthalmological deficits or patients with persistent ocular symptoms should, in particular, be followed with a low threshold for cutaneous SCC or PNI of recurrent disease. SCC metastasizing into the periocular tissues and orbit by neural invasion is rare and carries a poor prognosis. The urgency for a prompt diagnosis and evaluation by a multidisciplinary team is warranted to prevent untoward outcomes of this skin cancer. |
| Databáze: | OpenAIRE |
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