Cardiopulmonary vagal affarents in the monkey: A survey of receptor activity
| Autor: | J. P. Gilmore, Irving H. Zucker |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Male
medicine.medical_specialty Baroreceptor Sensory Receptor Cells Physiology Heart Ventricles Atrial Pressure Action Potentials Aorta Thoracic Blood Pressure Pressoreceptors Pulmonary stretch receptors Physiology (medical) Internal medicine medicine Animals Heart Atria Receptor business.industry Low pressure receptor zones Vagus Nerve Haplorhini Macaca mulatta Atrial volume receptors Pulmonary Stretch Receptors Endocrinology cardiovascular system Ventricular pressure Macaca Female Cardiology and Cardiovascular Medicine business Stretch receptor |
| Zdroj: | Basic Research in Cardiology. 72:392-401 |
| ISSN: | 1435-1803 0300-8428 |
| DOI: | 10.1007/bf02023598 |
| Popis: | A survey was made of vagal afferents whose endings originated in cardiopulmonary areas of the Rhesus monkey. Recordings of action potentials from single fiber preparations of the left cervical vagus were made in both open and closed chest monkeys. A total of 425 receptors were identified in sixteen animals. These consisted of 347 pulmonary stretch receptors (one of which increased its discharge during expiration), 42 aortic baroreceptors, 4 ventricular pressure receptors, 1 epicardial ventricular receptor, 7 type A atrial receptors and 24 type B atrial receptors. The response of each cardiovascular receptor was tested by altering the stimulus for their discharge. Aortic and ventricular baroreceptors increased their discharge in response to an increase in blood pressure induced by intravenous norepinephrine. Type A atrial receptors did not increase their discharge in response to an increase in atrial pressure during intravenous administration of isotonic saline, while type B atrial receptors did. The discharge of the latter became continuous following the intravenous administration of veratridine sulphate (20 microgram). It is concluded that the basic types of cardiopulmonary afferents exist in the non-human primate and that they respond similarly to those which have been demonstrated in lower species. |
| Databáze: | OpenAIRE |
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