Two-view digital breast tomosynthesis screening with synthetically reconstructed projection images: comparison with digital breast tomosynthesis with full-field digital mammographic images
| Autor: | Andriy I. Bandos, Unni Haakenaasen, Mina Izadi, Solveig Hofvind, Per Skaane, Ellen B. Eben, Ulrika Ekseth, Ingvild N. Jebsen, Mona Krager, Randi Gullien |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Breast Neoplasms Radiation Dosage Radiographic image interpretation Medicine Humans Mass Screening Radiology Nuclear Medicine and imaging Medical physics Computer vision Prospective Studies Registries Projection (set theory) Mass screening Early Detection of Cancer Aged business.industry Norway Digital Breast Tomosynthesis Full field Middle Aged Tomosynthesis Radiographic Image Enhancement Radiographic Image Interpretation Computer-Assisted Female Artificial intelligence business Mammography |
| Zdroj: | Radiology. 271(3) |
| ISSN: | 1527-1315 |
| Popis: | To compare the performance of two versions of reconstructed two-dimensional (2D) images in combination with digital breast tomosynthesis (DBT) versus the performance of standard full-field digital mammography (FFDM) plus DBT.This trial had ethical committee approval, and all participants gave written informed consent. Examinations (n = 24 901) in women between the ages of 50 and 69 years (mean age, 59.2 years) were interpreted prospectively as part of a screening trial that included independent interpretations of FFDM plus DBT and reconstructed 2D images plus DBT. Reconstructed 2D images do not require radiation exposure. Using analyses for binary data that accounted for correlated interpretations and were adjusted for reader-specific volume, two versions (initial and current) of reconstructed 2D images used during trial periods 1 (from November 22, 2010, to December 21, 2011; 12 631 women) and 2 (from January 20, 2012, to December 19, 2012; 12 270 women) were compared in terms of cancer detection and false-positive rates with the corresponding FFDM plus DBT interpretations.Cancer detection rates were 8.0, 7.4, 7.8, and 7.7 per 1000 screening examinations for FFDM plus DBT in period 1, initial reconstructed 2D images plus DBT in period 1, FFDM plus DBT in period 2, and current reconstructed 2D images plus DBT in period 2, respectively. False-positive scores were 5.3%, 4.6%, 4.6%, and 4.5%, respectively. Corresponding reader-adjusted paired comparisons of false-positive scores revealed significant differences for period 1 (P = .012) but not for period 2 (ratio = 0.99; 95% confidence interval: 0.88, 1.11; P = .85).The combination of current reconstructed 2D images and DBT performed comparably to FFDM plus DBT and is adequate for routine clinical use when interpreting screening mammograms. |
| Databáze: | OpenAIRE |
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