Hypertension and frailty in older adults
Autor: | Rafael Catoia Pulgrossi, Leonardo M. Torres, Mônica Sanches Yassuda, Ícaro S. Fernandez, Paula L. M. Castro, Ivan Aprahamian, Marina Maria Biella, Marília Funchal dos Santos, Olívia A. Pião, Eduardo Sassaki, Rafael Izbicki, Ana Camila N. Borges, Marcela M. Sassaki, Pedro A. Fontenele |
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Rok vydání: | 2017 |
Předmět: |
Male
Gerontology Activities of daily living Frail Elderly Endocrinology Diabetes and Metabolism Frailty syndrome Hypertension in the Elderly Comorbidity 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Risk Factors Weight loss Prevalence Internal Medicine medicine Humans Mass Screening Prospective Studies 030212 general & internal medicine Geriatric Assessment Aged Cause of death Aged 80 and over Frailty business.industry Blood Pressure Determination Odds ratio Prognosis medicine.disease Cross-Sectional Studies Blood pressure Hypertension Female medicine.symptom Cardiology and Cardiovascular Medicine business Body mass index Brazil |
Zdroj: | J Clin Hypertens (Greenwich) |
ISSN: | 1524-6175 |
DOI: | 10.1111/jch.13135 |
Popis: | The association between hypertension and frailty syndrome in older adults remains unclear. There is scarce information about the prevalence of hypertension among frail elderly patients or on its relationship with frailty. Up to one quarter of frail elderly patients present without comorbidity or disability, yet frailty is a leading cause of death. The knowledge and better control of frailty risk factors could influence prognosis. The present study evaluated: (1) the prevalence of hypertension in robust, prefrail, and frail elderly; and (2) factors that might be associated with frailty including hypertension. A cross-sectional study was conducted in 619 older adults at a university-based outpatient center. Study protocol included sociodemographic data, measures of blood pressure and body mass index, frailty screening according to the internationally validated FRAIL (fatigue, resistance, ambulation, illnesses, and loss of weight) scale, number of comorbidities, drug use assessment, physical activity, cognitive status, and activities of daily living. Ordinal logistic regression was used to evaluate factors associated with frailty. Prevalence of hypertension and frailty was 67.3% and 14.8%, respectively, in the total sample. Hypertension was more prevalent in the prefrail (72.5%) and frail (83%) groups than among controls (51.7%). Hypertension, physical activity, number of prescribed drugs, and cognitive performance were significantly associated with frailty status. Hypertension presented an odds ratio of 1.77 towards frailty (95% confidence interval, 1.21-2.60; P = .002). Hypertension was more prevalent in frail elderly patients and was significantly associated with frailty. Intensive control of hypertension could influence the trajectory of frailty, and this hypothesis should be explored in future prospective clinical trials. |
Databáze: | OpenAIRE |
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