Survey of extended-spectrum beta-lactamases in Escherichia coli isolates from a Portuguese hospital and characterisation of a novel class 1 integron (In60A) carrying the bla(CTX-M-9) gene
| Autor: | Aida Duarte, Maria José Salgado, A Brizio, Ana Rita Gonçalves, Luis Manuel Lito, Sergio Vasco, José Melo Cristino |
|---|---|
| Přispěvatelé: | Repositório da Universidade de Lisboa |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Microbiology (medical)
DNA Bacterial Male medicine.drug_class Antibiotics Integron medicine.disease_cause Microbiology beta-Lactam Resistance beta-Lactamases Integrons polycyclic compounds medicine Escherichia coli Humans Pharmacology (medical) Pharmacology & Pharmacy Insertion sequence Child Gene Escherichia coli Infections Genetics biology Portugal β lactamases Escherichia coli Proteins General Medicine biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Enterobacteriaceae Hospitals Infectious Diseases Child Preschool biology.protein Female Bacteria |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| Popis: | Between November 2001 and November 2004, 231 Escherichia coli isolates resistant to P-lactam antibiotics were identified. In 14 isolates, bla(TEM-24) (2 isolates), bla(TEM-52) (5 isolates) and bla(TEM-26) (7 isolates) were identified. In 145 E. coli isolates with the same M13 fingerprinting profile and the same resistance phenotype, the bla(CTX-M-15) gene was found in association with an insertion sequence ISEcp1. The bla(CTX-M-2) gene was identified in one E. coli isolate (290HSM), and in other E. coli isolate (246HSM) the bla(CTX-M-9) gene was contained in a new complex sull-type class 1 integron (named In60A). This is the first report of three cefotaximases (CTX-M-15, CTX-M-2 and CTX-M-9) in E. coli isolates from a Portuguese hospital. (c) 2006 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|