Association between early-stage chronic kidney disease and reduced choroidal thickness in essential hypertensive patients
| Autor: | Rossella Gaetani, Micol Terrasi, Giuseppe Mulè, Giuseppe Virone, Marco Guarneri, Maria Vadalà, Tiziana La Blasca, Massimo Castellucci, Giulia Guarrasi, Santina Cottone |
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| Přispěvatelé: | Mulè, Giuseppe, Vadalà, Maria, La Blasca, Tiziana, Gaetani, Rossella, Virone, Giuseppe, Guarneri, Marco, Castellucci, Massimo, Guarrasi, Giulia, Terrasi, Micol, Cottone, Santina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Physiology Urology Renal function 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Renal damage Internal Medicine medicine Humans 030212 general & internal medicine Prospective Studies Renal Insufficiency Chronic Aged Kidney Hypertensive eye disease business.industry Choroid Microcirculation Confounding Diabetic retinopathy Odds ratio Middle Aged medicine.disease eye diseases Confidence interval medicine.anatomical_structure Renal dysfunction Female sense organs Essential Hypertension Cardiology and Cardiovascular Medicine business Tomography Optical Coherence Kidney disease |
| Zdroj: | Hypertension research : official journal of the Japanese Society of Hypertension. 42(7) |
| ISSN: | 1348-4214 |
| Popis: | The introduction in the past few years of advanced optical coherence tomography (OCT) techniques has greatly increased our understanding of the choroid, which is the most important vascular layer of the eye. Our study aimed to assess choroidal thickness by using swept-source OCT (SS-OCT) in essential hypertensive patients (EHs) with and without early-stage chronic kidney disease (CKD). We enrolled 100 EHs, of whom 65 were without kidney damage, and 35 had stage 1-3 CKD. In all of the participants, SS-OCT and a routine biochemical workup were performed. Glomerular filtration rate (GFR) was estimated by the CKD Epidemiology Collaboration equation (eGFR). CKD was defined in agreement with the Kidney Disease Outcomes Quality Initiative Kidney Disease: Improving Global Outcomes 2002 guidelines. OCT measurements were performed according to the Early Treatment Diabetic Retinopathy Study (ETDRS) protocol, which divides the macula into nine subfields. The circular grid consists of three concentric rings. EHs with CKD showed thinner choroidal thicknesses than those without it (all p |
| Databáze: | OpenAIRE |
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