Optimization of femtosecond lasers using porcine and human donor corneas before in vivo use
| Autor: | Athanasios G. Marneris, Matthew J. Borr, Jenna E. Stoddard, Michael L. Keil |
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| Rok vydání: | 2017 |
| Předmět: |
Materials science
genetic structures Swine medicine.medical_treatment Corneal Stroma Keratomileusis Laser In Situ Keratomileusis 01 natural sciences Surgical Flaps law.invention 010309 optics 03 medical and health sciences 0302 clinical medicine law 0103 physical sciences medicine Animals Humans Inlay LASIK Laser Corneal inlay eye diseases Sensory Systems Ophthalmology Femtosecond Models Animal 030221 ophthalmology & optometry Surgery Lasers Excimer sense organs Biomedical engineering |
| Zdroj: | Journal of cataract and refractive surgery. 44(8) |
| ISSN: | 1873-4502 |
| Popis: | Purpose To demonstrate a safe and effective method of optimizing a femtosecond laser upon installation or for a new procedure before use on patients. In this case, specifically for optimizing settings for intrastromal corneal pocket creation for the presbyopic small-aperture corneal inlay (Kamra) and deep laser in situ keratomileusis (LASIK) flaps for the presbyopic hydrogel corneal inlay (Raindrop). Setting Keil LASIK Vision Center, Grand Rapids, Michigan, USA. Design Experimental study. Methods Human donor corneas were used to optimize femtosecond laser settings after initial optimization with porcine corneas. The laser used was the Femto LDV Z4. Results Pocket settings optimized for porcine corneas were 12.0 mm/s pocket and tunnel at 105% energy; whereas, settings optimized with human donor corneas were 13.0 mm/s pocket and tunnel at 110% energy. Settings optimized with human donor corneas were subsequently applied in vivo to create pockets for the small-aperture corneal inlay. Further adjustment of settings to 14.0 mm/s pocket at 110% energy was still necessary to optimize pockets. No change in settings was necessary when creating deeper corneal LASIK flaps (ie, the same settings could be used for flaps of 110 μm or 180 μm). Conclusions After settings were optimized for porcine corneas, further optimization was necessary before successful corneal incisions could be created in vivo for corneal pockets. No further optimization was required when creating deeper corneal flaps for the hydrogel inlay. It is important to emphasize that settings obtained and reported here are not applicable to other femtosecond lasers. |
| Databáze: | OpenAIRE |
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