New frontiers for cardiac PET: looking beyond mean transmural myocardial quantification
| Autor: | D. Daou |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Coronary artery disease Coronary circulation Myocardial perfusion imaging Ammonia Coronary Circulation Internal medicine Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging medicine.diagnostic_test business.industry Myocardial Perfusion Imaging Hypertrophic cardiomyopathy General Medicine Blood flow Cardiomyopathy Hypertrophic medicine.disease Stenosis medicine.anatomical_structure Cardiac PET Cardiology Female business Perfusion Blood Flow Velocity |
| Zdroj: | European Journal of Nuclear Medicine and Molecular Imaging. 42:1899-1902 |
| ISSN: | 1619-7089 1619-7070 |
| Popis: | In this issue of the journal, Sciagra et al. report on the use of N-ammonia (NH3) to recognize transmural perfusion abnormalities in patients with hypertrophic cardiomyopathy (HCM) [1]. The authors developed a method to quantify absolute blood flow in the subendocardial and subepicardial layers. This paper comes after a series of studies using Owater (H2 O) with cardiac positron emission tomography (PET) to split mean transmural myocardial perfusion into two layers (subendocardial and subepicardial) and conducted in patients having normal or increased left ventricular (LV) myocardial wall thickness: HCM, coronary artery disease (CAD), aortic stenosis and healthy controls [2–6]. The study by Sciagra et al. is of particular interest because it broadens the scope of application of cardiac PET to the use of a more widely available myocardial perfusion PET radiotracer NH3 for splitting mean transmural absolute myocardial wall perfusion into subendocardial and subepicardial components. This study provides the opportunity to raise some interesting points concerning cardiac PETand its potential for exploring new frontiers by splitting mean myocardial wall quantitative parameters into two layers. Clinical need to go beyond mean transmural myocardial parameters |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|