Hyperventilation and Spinal Reflexes
| Autor: | Arthur Taub, Luke M. Kkahata, Isao Sato |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Partial Pressure
Stimulation Motor Activity Lumbar Reflex Hyperventilation medicine Animals CATS business.industry Respiration Hemodynamics Spinal reflex Long-term potentiation Carbon Dioxide Spinal cord Anesthesiology and Pain Medicine medicine.anatomical_structure Spinal Cord Anesthesia Cats medicine.symptom Anesthesia Inhalation business |
| Zdroj: | Anesthesiology. 31:321-325 |
| ISSN: | 0003-3022 |
| DOI: | 10.1097/00000542-196910000-00006 |
| Popis: | The effects of hyperventilation upon dorsal-to-ventral-root spinal reflexes were evaluated in cats to determine whether passive hyperventilation produced during clinical anesthesia affects re-flexly-mediated motor activity. The results indicate that both monosynaptic and polysynaptic dorsal-to-ventral-root spinal reflexes arc facilitated by hyperventilation, monosynaptic responses more than polysynaptic responses. Monosynaptic responses enhanced by posttetanic potentiation were further facilitated by hyperventilation. Transection of the spinal cord rostral to the site of spinal reflex recording did not abolish the facilitatory effect of hyperventilation upon the spinal reflexes. When the end-expiratory CO2 was kept at control levels (4.0 ± 0.2 per cent) during hyperventilation, reflex facilitation was not seen. It is concluded that hyperventilation facilitates the feline lumbar spinal reflex through the effect of hypocarbia upon the lumbar spinal reflex are rather than through respiratory reflex activity. The relaxant effects of hyperventilation must be caused by means other than the direct suppression of spinal reflex action as defined by electrical stimulation of dorsal roots. |
| Databáze: | OpenAIRE |
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