HIGH ALTITUDE AND VENOUS THROMBOSIS: FREQUENCY AND RISK FACTORS
| Autor: | Manzur Qadir, Ghassan Omair, Qamar Un-Nisa Choudry, Tariq Mehmood Satti, Syed Kamran Mehmood, Raheel Iftikhar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Medicine (General) medicine.diagnostic_test business.industry Hematocrit Effects of high altitude on humans medicine.disease Thrombosis embolism Venous thrombosis R5-920 Embolism Internal medicine polycythemia Epidemiology Cardiology Medicine Cerebral venous sinus thrombosis business Prospective cohort study thrombosis |
| Zdroj: | Pakistan Armed Forces Medical Journal, Vol 71, Iss 1, Pp 107-11 (2021) |
| ISSN: | 2411-8842 0030-9648 |
| Popis: | Objective: To determine the effect of high altitude on frequency and risk factors of venous thrombosis inindividuals ascending to high altitude Study Design: Cross-sectional analytical study. Place and Duration of Study: Armed Forces Bone Marrow Transplant Centre, Combined Military HospitalSkardu, from Apr 2015 to Aug 2018. Methodology: High Altitude was taken as height equal to or more than 8000 feet. Polycythemia as hemoglobin>16.5 g/dl OR hematocrit >49%. Medical records of all patients evacuated from high altitude through CombinedMilitary Hospital Skardu were analyzed retrospectively. A proforma was designed to include necessary variables. Results: We evaluated medical records of 539 individuals and found frequency of 86 (15.9%) for venous thromboembolism (VTE) at high altitude. Cerebral venous sinus thrombosis (CVST) was most common thrombotic complication seen in 39 patients (46%). Majority of thrombotic episodes occurred at >18000 feet (likelihood ratio (LR) 5.99, p-value 0.009). Majority of thrombotic episodes 34 (39%) occurred within first 45 days of ascent to high altitude. Thrombosis was linked to smoking 47 (55%) (likelihood ratio 21.3 and p-value |
| Databáze: | OpenAIRE |
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