Doppler velocimetry of the fetal middle cerebral artery and other parameters of fetal well-being in neonatal survival during pregnancies with placental insufficiency
Autor: | Yamamoto Nomura, Roseli Mieko, Niigaki, Juliana Ikeda, Horigome, Flávia Thiemi, Vieira Francisco, Rossana Pulcineli, Zugaib, Marcelo |
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Jazyk: | angličtina |
Předmět: |
Male
Ultrassonografia Middle cerebral artery Umbilical arteries Cordão umbilical Ultrasonography Prenatal Insuficiência placentária Pregnancy Fetal hypoxia Laser-Doppler Flowmetry Humans Prospective Studies Umbilical cord General Environmental Science Ultrasonography Analysis of Variance Infant Newborn Doppler Prognosis Survival Analysis Placental insufficiency Artérias umbilicais Hipóxia fetal Artéria cerebral média General Earth and Planetary Sciences Female Blood Flow Velocity |
Zdroj: | Revista da Associação Médica Brasileira (English Edition). (4):392-399 |
ISSN: | 2255-4823 |
DOI: | 10.1016/S2255-4823(13)70493-4 |
Popis: | ObjectiveTo study the Doppler velocimetry of the fetal middle cerebral artery in pregnancies complicated by placental insufficiency, and to verify its role in the prognosis of neonatal survival.MethodsThis was a prospective study of 93 pregnant women with diagnosis of placental insufficiency detected before the 34th week of pregnancy. Placental insufficiency was characterized by abnormal umbilical artery (UA) Doppler (> 95th percentile). The following parameters were analyzed: umbilical artery (UA) pulsatility index (PI); middle cerebral artery (MCA) PI; brain-placenta ratio – BPR (MCA-PI/UA-PI); MCA peak systolic velocity (MCA-PSV); and PI for veins (PIV) of ductus venosus (DV). The parameters were analyzed in terms of absolute values, z-scores (standard deviations from the mean), or multiples of the median (MoM). The outcome investigated was neonatal death during the hospitalization period after birth.ResultsOf the 93 pregnancies analyzed, there were 25 (26.9%) neonatal deaths. The group that died, when compared to the survival group, presented a significant association with the diagnosis of absent or reversed end-diastolic flow (88% vs. 23.6%, p |
Databáze: | OpenAIRE |
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