Carotid artery longitudinal wall motion alterations associated with metabolic syndrome and insulin resistance
| Autor: | Mika Kähönen, Markus Juonala, Tomi Laitinen, Tiina M. Laitinen, Heikki Yli-Ollila, S. Helena Taivainen, Olli T. Raitakari |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Carotid Artery Common Physiology 030204 cardiovascular system & hematology Carotid Intima-Media Thickness 03 medical and health sciences 0302 clinical medicine Insulin resistance Risk Factors Physiology (medical) medicine.artery Internal medicine medicine Hyperinsulinemia Humans Common carotid artery Metabolic Syndrome business.industry 030229 sport sciences General Medicine medicine.disease Obesity Carotid Arteries Arterial stiffness Cardiology Biomarker (medicine) Insulin Resistance Metabolic syndrome business Homeostasis |
| Zdroj: | Clinical Physiology and Functional Imaging. 41:199-207 |
| ISSN: | 1475-097X 1475-0961 |
| DOI: | 10.1111/cpf.12687 |
| Popis: | BACKGROUND AND AIMS Our objective was to study relationships between the new biomarker of vascular health, carotid artery longitudinal wall motion (CALM) and metabolic syndrome (MetS). METHODS Carotid ultrasound and assessment of MetS and its components were performed with 281 subjects aged 30-45 years. In the longitudinal motion analysis, the amplitude of motion and the antegrade-oriented and retrograde-oriented components of motion between the intima-media complex and adventitial layer of the common carotid artery wall were assessed. RESULTS Metabolic syndrome, according to the harmonized criteria, was detected in 53 subjects (19%). MetS was significantly associated with increased antegrade and decreased retrograde longitudinal motion in the carotid artery wall. Augmented antegrade amplitude of longitudinal motion was associated with obesity (β = 0.149, p |
| Databáze: | OpenAIRE |
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