Sarcoidosis with upper respiratory tract involvement
Autor: | Chiara Ginanneschi, Daniele Nuti, Paola Rottoli, Elena Bargagli, Marcella Cintorino, Giuseppe Caruso, Carmelina Chidichimo |
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Rok vydání: | 2006 |
Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Larynx medicine.medical_specialty High-resolution computed tomography Pathology Systemic disease Sarcoidosis Biopsy Laryngeal Diseases stomatognathic system Nose Diseases otorhinolaryngologic diseases medicine Humans Parotid Gland Nose Aged medicine.diagnostic_test business.industry Mucous membrane Middle Aged medicine.disease Dermatology Parotid gland Early Diagnosis medicine.anatomical_structure Female Parotid Diseases business Upper respiratory tract Respiratory tract |
Zdroj: | Respiratory Medicine. 100:253-257 |
ISSN: | 0954-6111 |
DOI: | 10.1016/j.rmed.2005.04.018 |
Popis: | SummaryThe aim of the study was to investigate the upper respiratory tract as a site of extrapulmonary sarcoidosis. Diagnosis of sarcoidosis with upper respiratory tract involvement was performed on the basis of clinical, laboratory, radiographic and histological evidence and by excluding other granulomatous diseases in eight patients followed by the Sarcoidosis Regional Reference Centre pneumologists in collaboration with an experienced ENT specialist at Siena University. In five cases, sarcoidosis was localized in the parotid glands, in the other three subjects larynx, nasopharynx and nose were involved. In four patients parotid gland, nasopharynx and upper respiratory tract mucous membrane involvement was the only clinical manifestation at onset of the disease.Upper respiratory tract involvement should be suspected in all patients with systemic sarcoidosis and in patients with persistent upper respiratory tract symptoms of unknown cause. What a general practitioner should do as not to miss SURT is underlined. Interdisciplinary management and collaboration are of paramount importance for rapid diagnosis and to avoid the possible complications of this form. |
Databáze: | OpenAIRE |
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