Enantioselective fluorination of 3-indolinone-2-carboxylates with NFSI catalyzed by chiral bisoxazolines

Autor:	B. V. Subba Reddy, B. Sridhar, Swarnayu Banik, Tanmoy Sahoo
Rok vydání:	2021
Předmět:	Chemistry Organic Chemistry Electrophilic fluorination Enantioselective synthesis Physical and Theoretical Chemistry Biochemistry Combinatorial chemistry Catalysis
Zdroj:	Organic & Biomolecular Chemistry. 19:6085-6091
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d1ob00144b
Popis:	A chiral Cu(i)-bisoxazoline complex catalyzed enantioselective electrophilic fluorination of 3-indolinone-2-carboxylates with NFSI has been accomplished to produce chiral 2-fluoro-3-indolinone-2-carboxylates in good yields with excellent enantioselectivities. This is the first report on the enantioselective fluorination of 2-substituted 3-indolinones using a chiral Cu(i)-bisoxazoline complex.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c4d7811f57d59d0b8c9dd38ec3684f https://doi.org/10.1039/d1ob00144b Zobrazit plný text záznamu