Small pancreatic neuroendocrine tumors: Resect or enucleate?
| Autor: | Henry A. Pitt, Mohamed A. Adam, Amblessed E. Onuma, Joal D. Beane, Amer H. Zureikat, Andrew Billderback, Jeffrey D. Borrebach |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Operative Time Enucleation 030230 surgery Neuroendocrine tumors Pancreaticoduodenectomy Resection 03 medical and health sciences Pancreatectomy Postoperative Complications 0302 clinical medicine medicine Humans Blood Transfusion Practice Patterns Physicians' Pancreas Aged Retrospective Studies business.industry General Medicine Length of Stay Middle Aged medicine.disease Tumor Burden Surgery Pancreatic Neoplasms Neuroendocrine Tumors Treatment Outcome 030220 oncology & carcinogenesis Operative time Female Distal pancreatectomy business Organ Sparing Treatments |
| Zdroj: | The American Journal of Surgery. 222:29-34 |
| ISSN: | 0002-9610 |
| DOI: | 10.1016/j.amjsurg.2020.12.013 |
| Popis: | The aim of this analysis is to compare the postoperative outcomes of resection and enucleation of small pancreatic neuroendocrine tumors (PNETs).The 2014-17 American College of Surgeons-NSQIP dataset was queried. Patients undergoing pancreatoduodenectomy (N = 297) or distal pancreatectomy (N = 712) for nonfunctional, small PNETs (T1/T2) were compared to 127 patients (11%) who were enucleated.Operative time (170 vs 261, p 0.01) and transfusions were less in the enucleation cohort (1.6% vs 6.7% p 0.01). There was no difference in postoperative pancreatic fistulas, but morbidity was lower in enucleated patients (36.2% vs 48.7% p 0.01). Fifteen resected patients died postoperatively (1.5%) while all enucleated patients survived (p = 0.058). Mean postoperative length of stay was shorter after enucleation (5.7 vs 7.2 days p 0.01).Enucleation of PNETs is performed in only 11% of patients, but takes less time, requires fewer transfusions, and is associated with reduced morbidity and shorter length of stay than resection. |
| Databáze: | OpenAIRE |
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