Long-term surface cortical cerebral blood flow monitoring in temporal lobe epilepsy
| Autor: | D M Labiner, D Talwar, D D Patton, Kalarickal J. Oommen, L. P. Carter, Martin E. Weinand |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Thermodilution Temporal lobe Epilepsy Internal medicine Medicine Humans Ictal Cerebral perfusion pressure Child Dominance Cerebral Monitoring Physiologic Cerebral Cortex Brain Mapping business.industry Electroencephalography Signal Processing Computer-Assisted Human brain Middle Aged medicine.disease Long-Term Care Temporal Lobe Frontal Lobe medicine.anatomical_structure Frontal lobe Cerebral blood flow Epilepsy Temporal Lobe Cerebral cortex Cardiology Surgery Female Neurology (clinical) business Rheology Blood Flow Velocity |
| Zdroj: | Neurosurgery. 35(4) |
| ISSN: | 0148-396X |
| Popis: | Long-term subdural surface cortical cerebral blood flow (CBF) and electrocorticographic monitoring was performed in 12 patients with complex partial seizures. A total of 40 seizures were analyzed. Baseline CBF values from nonepileptic and epileptic temporal lobe (mean +/- standard error) were 60.0 +/- 1.0 and 50.2 +/- 1.8 ml/100 g per minute, respectively (P0.05). In general, clinical seizure onset was preceded by a 20-minute preictal CBF increase from baseline in the epileptic temporal lobe. Peak early postictal CBF values of nonepileptic and epileptic temporal lobes were 57.7 +/- 13.3 and 89.0 +/- 21.7 ml/100 g per minute (P0.05) at 5.2 +/- 2.2 and 2.4 +/- 1.0 minutes (P0.05) after clinical seizure onset, respectively. Statistically significant differences between nonepileptic and epileptic temporal lobe CBF were detected at 50 minutes (74.0 +/- 14.2 and 37.5 +/- 9.2 ml/100 g per minute, respectively; P0.05) and 60 minutes (75.6 +/- 13.6 and 36.1 +/- 8.5 ml/100 g per minute, respectively; P0.05) postictal. The data suggest that the optimal times for CBF analysis to differentiate epileptic from nonepileptic temporal lobe are 1) during the interictal period and 2) late (50 to 60 minutes) postictal. The results of this study should improve the understanding of the dynamic cerebral perfusion patterns in the epileptic human brain. |
| Databáze: | OpenAIRE |
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