Correction to: Maternal and neonatal outcomes in mothers with diabetes mellitus in Qatari population
Autor: | Saad Shahbal, Sunitha D'Souza, Nada Y S Matani, Ravi Agarwal, Razan M Masri, Mohammad A A Bayoumi, Einas E Elmalik, Ashraf I Gad, Mohamed A Hendaus, Prem Chandra, Lisa J. Langtree, Noimot O Olayiwola, Mohamed Sobhy Bakry, Manal M Masri |
---|---|
Rok vydání: | 2021 |
Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Population Pregnancy in Diabetics Reproductive medicine MEDLINE Gestational Age Body Mass Index Congenital Abnormalities Fetal Macrosomia Cohort Studies Pregnancy Diabetes mellitus Diabetes Mellitus medicine Birth Weight Humans education Qatar Retrospective Studies Glycated Hemoglobin education.field_of_study Cesarean Section Maternal and child health business.industry Infant Newborn Correction Obstetrics and Gynecology Gynecology and obstetrics medicine.disease Diabetes Gestational Cross-Sectional Studies Neonatal outcomes RG1-991 Female business Maternal Age |
Zdroj: | BMC Pregnancy and Childbirth, Vol 21, Iss 1, Pp 1-1 (2021) BMC Pregnancy and Childbirth |
ISSN: | 1471-2393 |
Popis: | Diabetes Mellitus (DM) is a major cause of maternal, fetal, and neonatal morbidities. Our objective was to estimate the effect of both pre-pregnancy and gestational DM on the growth parameters of newborns in the Qatari population.In this population-based cohort study, we compared the data of neonates born to Qatari women with both pre-pregnancy and gestational diabetes mellitus in 2017 with neonates of healthy non-diabetic Qatari women.Out of a total of 17020 live births in 2017, 5195 newborns were born to Qatari women. Of these, 1260 were born to women with GDM, 152 were born to women with pre-pregnancy DM and 3783 neonates were born to healthy non-diabetic (control) women. The prevalence of GDM in the Qatari population in 2017 was 24.25%. HbA1C% before delivery was significantly higher in women with pre-pregnancy DM (mean 6.19 ± 1.15) compared to those with GDM (mean 5.28 ± 0.43) (P0.0001). The mean birth weight in grams was 3066.01 ± 603.42 in the control group compared to 3156.73 ± 577.88 in infants born to women with GDM and 3048.78 ± 677.98 in infants born to women with pre-pregnancy DM (P0.0001). There was no statistically significant difference regarding the mean length (P= 0.080), head circumference (P= 0.514), and rate of major congenital malformations (P= 0.211). Macrosomia (Birth weight4000 gm) was observed in 2.7% of the control group compared to 4.8% in infants born to women with GDM, and 4.6% in infants born to women with pre-pregnancy DM (P= 0.001). Multivariate logistic regression analysis demonstrated that higher maternal age (adjusted OR 2.21, 95% CI 1.93, 2.52, P0.0001), obesity before pregnancy (adjusted OR 1.71, 95% CI 1.30, 2.23, P0.0001), type of delivery C-section (adjusted OR 1.25, 95% CI 1.09, 1.44, P=0.002), and body weight to gestational age LGA (adjusted OR 2.30, 95% CI 1.64, 2.34, P0.0001) were significantly associated with increased risk of GDM.Despite the multi-disciplinary antenatal diabetic care management, there is still an increased birth weight and an increased prevalence of macrosomia among the infants of diabetic mothers. More efforts should be addressed to improve the known modifiable factors such as women's adherence to the diabetic control program. Furthermore, pre-pregnancy BMI was found to be significantly associated with gestational DM, and this is a factor that can be addressed during pre-conceptional counseling. |
Databáze: | OpenAIRE |
Externí odkaz: |