Evaluation and Validation of Four Scoring Systems: the APACHE IV, SAPS III, MPM0 II, and ICMM in Critically Ill Cancer Patients
| Autor: | Satish V Sarode, Amit M Narkhede, Natesh R Prabu, Atul P Kulkarni, Jigeeshu V Divatia, Harish K Chaudhari, Suhail Sarwar Siddiqui |
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| Rok vydání: | 2019 |
| Předmět: |
Acute physiology and chronic health evaluation IV
medicine.medical_specialty Simplified acute physiology score 3 SAPS III Critical Care and Intensive Care Medicine Tertiary care law.invention law Mortality probability models II at 0 hours Internal medicine Medicine Simplified Acute Physiology Score Severity-of-illness scoring systems Prospective cohort study Cancer business.industry Critically ill Intensive care unit mortality medicine.disease Intensive care unit cancer mortality model Intensive care unit Health evaluation Original Article Intensive care unit outcome business |
| Zdroj: | Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine |
| ISSN: | 1998-359X 0972-5229 |
| Popis: | Background and aims To evaluate and validate four severity-of-illness scores, acute physiology and chronic health evaluation IV (APACHE IV), simplified acute physiology score III (SAPS III), mortality probability models II at 0 hours (MPM0 II), and ICU cancer mortality model (ICMM), in a prospective cohort of critically ill cancer patients. Materials and methods Single-center, prospective observational study performed in a 14-bedded combined medical–surgical ICU of a tertiary care cancer center of India, from July 2014 to November 2015. Score performance was judged by discrimination and calibration, using the area under receiver–operating characteristics (ROC) curve and Hosmer–Lemeshow goodness-of-fit test, respectively. Results A total of 431 patients were included in the study. Intensive care unit (ICU) and hospital mortality were 37.4% and 41.1%, respectively. The area under ROC curve for APACHE IV, SAPS III, MPM0 II, and ICMM were 0.73, 0.70, 0.67, and 0.67, respectively. Calibration as calculated by Hosmer–Lemeshow analysis type C statistics for APACHE IV, SAPS III, MPM0 II, and ICMM shows good calibration with Chi-square values of 5.32, 9.285, 9.873, and 9.855 and p values of 0.723, 0.319, 0.274, and 0.275, respectively. Conclusion All the four models had moderate discrimination and good calibration. However, none of the mortality prediction models could accurately discriminate between survivors and nonsurvivors in our patients. How to cite this article Siddiqui SS, Narkhede AM, Kulkarni AP, Prabu NR, Chaudhari HK, Divatia JV, et al. Evaluation and Validation of Four Scoring Systems: the APACHE IV, SAPS III, MPM0 II, and ICMM in Critically Ill Cancer Patients. Indian J Crit Care Med 2020;24(4):263–269. |
| Databáze: | OpenAIRE |
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