Intramolecular trans-Carbocarbonation of Internal Alkynes by a Cascade of Formal anti-Carbopalladation/Cyclopropanol Opening
| Autor: | Peter G. Jones, Andreas Reding, Daniel B. Werz |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Double bond 010405 organic chemistry Stereochemistry Alkene Organic Chemistry 010402 general chemistry Ring (chemistry) 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound chemistry Cascade reaction Cascade Cyclopropanol Yield (chemistry) Intramolecular force Physical and Theoretical Chemistry |
| Zdroj: | Organic Letters. 20:7266-7269 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | An intramolecular cascade reaction consisting of a formal anti-carbopalladation terminated by the ring-opening of a cyclopropanol unit is presented. The products, which involve tetrasubstituted alkene units embedded in an oligocyclic ring system, are generated in moderate to excellent yield. The opening of the cyclopropanol unit leads to a keto group in the γ-position to the emerging double bond. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|