Gene Aging Nexus: a web database and data mining platform for microarray data on aging
| Autor: | Sudip Pulapura, Michael R. Mehan, Chi Hsien Chiu, Fei Pan, Caleb E. Finch, Kangyu Zhang, Kiran Kamath, Xianghong Jasmine Zhou, Michael S. Waterman, Juan Nunez-Iglesias |
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| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Aging
Biology computer.software_genre 03 medical and health sciences Mice User-Computer Interface 0302 clinical medicine Resource (project management) Research community Databases Genetic Genetics Microarray databases Animals Humans 030304 developmental biology Oligonucleotide Array Sequence Analysis 0303 health sciences Internet business.industry Microarray analysis techniques Gene Expression Profiling Articles Rats Gene expression profiling ComputingMethodologies_PATTERNRECOGNITION Gene chip analysis The Internet Data mining business computer Nexus (standard) 030217 neurology & neurosurgery Software |
| Zdroj: | Nucleic Acids Research |
| ISSN: | 1362-4962 0305-1048 |
| Popis: | The recent development of microarray technology provided unprecedented opportunities to understand the genetic basis of aging. So far, many microarray studies have addressed aging-related expression patterns in multiple organisms and under different conditions. The number of relevant studies continues to increase rapidly. However, efficient exploitation of these vast data is frustrated by the lack of an integrated data mining platform or other unifying bioinformatic resource to enable convenient cross-laboratory searches of array signals. To facilitate the integrative analysis of microarray data on aging, we developed a web database and analysis platform 'Gene Aging Nexus' (GAN) that is freely accessible to the research community to query/analyze/visualize cross-platform and cross-species microarray data on aging. By providing the possibility of integrative microarray analysis, GAN should be useful in building the systems-biology understanding of aging. GAN is accessible at http://gan.usc.edu. |
| Databáze: | OpenAIRE |
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