Control of flow of fetal lung fluid at the laryngeal outlet
| Autor: | Forrest H. Adams, Bernard Towers, Donald T. Desilets |
|---|---|
| Rok vydání: | 1967 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Sling (implant) Amniotic fluid Physiology Respiratory System Contrast Media Epiglottis Epiglottic Cartilage Surface-Active Agents Fetus Pregnancy otorhinolaryngologic diseases medicine Animals Amnion Lung Nose Sheep business.industry Pharynx Laryngeal Nerves Anatomy respiratory system Surgery Radiography Trachea medicine.anatomical_structure Respiratory Physiological Phenomena Sphincter Female Larynx Airway business |
| Zdroj: | Respiration Physiology. 2:302-309 |
| ISSN: | 0034-5687 |
| DOI: | 10.1016/0034-5687(67)90035-7 |
| Popis: | Lambs near term with placental circulations intact were delivered by cesarean section. Cineroentgenograms of contrast material injected into the trachea demonstrated the presence of a sphincter mechanism at the laryngeal outlet. The sphincter opened periodically and allowed the lung fluid to be discharged into the nose and pharynx where it was swallowed. The mechanism consists of two large arytenoid cartilages which are held together and up against the back of the epiglottic cartilage by contraction of a muscular sling comprising thyro-arytenoid and inter-arytenoid muscles. Material injected into the nose or mouth did not enter the trachea except following occlusion of the umbilical cord. Sectioning the recurrent laryngeal nerves paralysed the muscle component of the sphincter. The mechanism probably aids in lung growth by maintaining a positive intraluminal pressure, and assists in the retention of lung surfactant. It also acts as a barrier to the ingress of mucus and amniotic fluid in utero into the future airway. |
| Databáze: | OpenAIRE |
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