Emergence of a novel macrolide-resistant Streptococcus pyogenes emm53 strain
Autor: | Motlová J, P. Kriz, V. Jakubu, Straková L, Urbásková P |
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Rok vydání: | 2007 |
Předmět: |
Adult
Microbiology (medical) Adolescent Tetracycline Antibiotic resistance Streptococcus pyogenes multilocus sequence typing Biology medicine.disease_cause Microbiology Drug Resistance Bacterial medicine Pulsed-field gel electrophoresis Humans Typing Child Antibacterial agent Aged Aged 80 and over Streptococcus group A streptococcus Infant Newborn Infant General Medicine Middle Aged Anti-Bacterial Agents Electrophoresis Gel Pulsed-Field Erythromycin Infectious Diseases pulsed-field gel electrophoresis Child Preschool emm type Multilocus sequence typing medicine.drug |
Zdroj: | Clinical Microbiology and Infection. 13(4):443-445 |
ISSN: | 1198-743X |
DOI: | 10.1111/j.1469-0691.2006.01658.x |
Popis: | An unusual emm53, T-28/T-non-typeable, iMLSB phenotype clone represented a substantial proportion (28.6%) of invasive erythromycin-resistant group A streptococcus (GAS) isolates in the Czech Republic during 2003. Clonal analysis of emm53 isolates between 2001 and 2004 revealed four pulsed-field gel electrophoresis (PFGE) patterns and two emm subtypes. Isolates produced identical PFGE patterns regardless of their invasiveness and/or tetracycline resistance. Multilocus sequence typing classified all isolates as ST340. An ST5 (emm83) isolate, a potential ancestor of ST340, was isolated in the Czech Republic from an impetigo patient in 1988. The Czech emm53/ST340 isolates shared only three of seven alleles with the original Lancefield emm53/ST11 isolate. |
Databáze: | OpenAIRE |
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