The formation process of button ulcers in pigs experimentally infected with a subgenotype 2.1 isolate of classical swine fever virus
| Autor: | Chiho Kushida, Mariko Ochiai, Mikio Oidemizu, Takao Nagasaka, Kasumi Sudo, Atsushi Yamamoto, Akito Saito, Maiko Yamashita, Manabu Yamada, Kinya Yamamoto, Shoko Iwamoto, Hajime Sakaki |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Pathology Necrosis Swine 040301 veterinary sciences button ulcer Virus Classical Swine Fever 0403 veterinary science 03 medical and health sciences Japan medicine Animals Ulcer 030304 developmental biology Swine Diseases 0303 health sciences Gastrointestinal tract General Veterinary biology business.industry 04 agricultural and veterinary sciences Note biology.organism_classification Lymphatic system herniation of crypt Classical Swine Fever Virus Classical swine fever histopathology Immunohistochemistry Histopathology medicine.symptom business |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| Popis: | We evaluated the role of classical swine fever virus (CSFV) in the formation of button ulcers in the mucosa of the gastrointestinal tract. Histopathological and immunohistochemical analyses of pigs experimentally infected with a subgenotype 2.1 isolate of CSFV, which was isolated in Japan in 2019, revealed follicular necrosis in the submucosal mucosa-associated lymphoid tissue and herniation of crypts as factors that contribute to the development of button ulcers during CSFV infection. These findings indicate that CSFV induces follicular necrosis and is one of the causative agents of button ulcers in pigs. |
| Databáze: | OpenAIRE |
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