Prevention of inappropriate ICD shocks in patients with Brugada syndrome
| Autor: | Florian Streitner, Christian Veltmann, Rainer Schimpf, Nina Schoene, Martin Borggrefe, Christian Wolpert, Juergen Kuschyk |
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| Rok vydání: | 2009 |
| Předmět: |
Tachycardia
Adult Male medicine.medical_specialty medicine.medical_treatment Sudden cardiac death Internal medicine medicine Tachycardia Supraventricular Humans In patient cardiovascular diseases Prospective Studies Prospective cohort study Brugada syndrome Brugada Syndrome business.industry General Medicine Middle Aged Implantable cardioverter-defibrillator medicine.disease Defibrillators Implantable Death Sudden Cardiac Shock (circulatory) Ventricular fibrillation Ventricular Fibrillation Cardiology Equipment Failure Female medicine.symptom Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | Clinical research in cardiology : official journal of the German Cardiac Society. 99(1) |
| ISSN: | 1861-0692 |
| Popis: | In Brugada syndrome implantable cardioverter defibrillator (ICD) therapy is associated with a high rate of inappropriate therapies, mainly due to supraventricular tachyarrhythmias (SVT) (2.7-14.1%/year). Aim of the present study was to evaluate a single ventricular fibrillation (VF) detection zone with a high cut-off rate with respect to prevention of inappropriate ICD shock due to SVT and safety of this programming.Sixty-one consecutive patients (mean age 42.6 +/- 12.9 years; 41 males) diagnosed with Brugada syndrome and implanted with an ICD were included. ICDs were prospectively programmed with a single VF detection zone and a cut-off rate of 222 beats/minute (bpm). A maximum of six shocks with the maximal shock energy were programmed. The minimal follow-up was 1 year.During a follow-up of 47.6 +/- 23.1 months seven patients (2.91%/year) received appropriate ICD shocks. No patient suffered from syncope or died. Five patients (2.07%/year) received inappropriate ICD shocks: four patients due to T-wave oversensing and only one patient (0.4%/year) due to SVT (atrial fibrillation with a ventricular rate of222 bpm).Programming of a single, high-rate VF zone in patients with Brugada syndrome and an implanted defibrillator is safe. Such programming may be associated with reduced inappropriate defibrillator discharges. A single detection zone with a high VF cut-off rate can be recommended in patients with Brugada syndrome. |
| Databáze: | OpenAIRE |
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