GENETIC CONTROLS OVER ACTIVITIES OF TYROSINASE AND DOPACHROME CONVERSION FACTOR IN MURINE MELANOCYTES
| Autor: | Catherine Woolley, Phil Pendergast, M. Lynn Lamoreux |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Tyrosinase
Gene Conversion Mice Inbred Strains Investigations Biology Melanocyte Mice Pigment chemistry.chemical_compound Species Specificity Genetics medicine Animals Gene conversion Catechol oxidase chemistry.chemical_classification Monophenol Monooxygenase Mice Mutant Strains Intramolecular Oxidoreductases Kinetics medicine.anatomical_structure Enzyme Genes chemistry Biochemistry visual_art visual_art.visual_art_medium Dopachrome biology.protein Melanocytes Specific activity Catechol Oxidase |
| Zdroj: | Genetics. 113:967-984 |
| ISSN: | 1943-2631 |
| DOI: | 10.1093/genetics/113.4.967 |
| Popis: | We evaluated the three catalytic activities of tyrosinase and one activity of dopachrome conversion factor (DCF) in extracts made from skins of 6-day-old yellow and nonyellow mice. At least one of the catalytic activities of tyrosinase and of DCF correlate with the color of pigment being produced in the hair follicles of the mice. We use these data to evaluate existing hypotheses about the mechanism of the interacting genetic controls over melanogenesis. |
| Databáze: | OpenAIRE |
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